In 2020, the second meta-analysis only focused on stages IB2 and II cervical cancers and was thus limited to 5 studies, including 2 case–control studies and only 1275 patients, with a nonsignificant trend for a 40% reduction in the risk of death with neoadjuvant chemotherapy [ 50 ].
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Sensitivity and Subgroup Analysis The sensitivity analysis indicated a nonsignificant trend towards lower 90-day mortality in centers with an annual pancreatoduodenectomy case volume above the median (70 per year), total DP-CAR volume above 5, and procedure year after 2008 (see Supplement 2).
of FACS-purified pancreatic β-cells from four T1D patients and thirteen nondiabetic individuals showed no changes in JAZF1 or GARS1 expression and a nonsignificant trend for reduced DARS1 levels in T1D β-cells [ 130 ].
For the posterior subgroup, only the direct comparison between clipping and coiling was available (OR, 4.85 [95% CI, 0.28–82.57]), suggesting a nonsignificant trend that clipping may be associated with higher mortality, but this estimate was very imprecise and based on limited data.
Pretreatment with dexa significantly prevented the upregulation of M1 (CD80 + /CCR2 + ) cells induced by LPS (0.7 ± 0.3% versus 3.0 ± 1.0%, p < 0.05, n = 6; Figures 2(a) and 2(b) ), whereas a nonsignificant trend of inhibition was observed for GG9 and CLI-095.
There was a nonsignificant trend toward greater estimated glomerular filtration rate decline in the placebo group compared to either of the fresolimumab-treated arms up to day 252.
While patients with ccRCC and pRCC had an equal proportion of recurrences, patients with chRCC had a nonsignificant trend for fewer recurrences.
However, a nonsignificant trend toward better survival was observed in moderately differentiated tumors compared with poorly differentiated ones, likely due to the limited sample size.
There was a nonsignificant trend in improved patient self-reported COC in the intervention group over the 3-month study period [ 8 ].
A nonsignificant trend toward an increase in CPSD with age was observed.
When performing these experiments without MC3T3-E1 cells, a pronounced increase in absorbance in the DFO treated group was observed ( Figure 1(b) ) while this was only observed as a nonsignificant trend in the presence of cells.
Our results also identified a nonsignificant trend indicating PCT could be of greater value in sepsis patients than in patients without sepsis.
Interestingly, there was a nonsignificant trend toward better vessel healing in the antiplatelet group, suggesting a potential benefit in younger patients [ 23 , 62 ].
We found a nonsignificant trend toward a reduced PAT/PET ratio in ESAM −/− mice ( Fig. 1 , A and B ), and no changes were observed in the Fulton index compared with WT animals ( Fig. 1C ).
These results indicate that although the hazard ratio (HR) in the lower MHR group was <1, the CI crossed unity and statistical significance was not achieved ( P = .2467), suggesting only a nonsignificant trend.
26 However, this was a retrospective study with a smaller sample size (n = 58) and low event rates, and there was a nonsignificant trend towards higher TR recurrence rates in those with transvalvular lead implantation compared with those without.
However, this meta-analysis demonstrated a nonsignificant trend toward risk of stroke (RR 1.37; 0.80–2.34), and significant increase in the risk of venous thromboembolism (VTE) (RR 1.74; 1.11–2.73) [ 95 ] A meta-analysis of effects of oral versus transdermal estrogen indicated that among women using estrogen-only preparations, oral but not transdermal preparations increased VTE risk (RR 1.48, 1.39–1.58; RR 0.97, 95% CI 0.87–1.09, respectively) [ 96 •].
While a nonsignificant trend toward higher frequencies of this subset was observed in both NL and PL skins compared to HS, interpatient variability was considerable (fig.
Regarding psychosocial history, nearly 40% of the cohort had a history of a mental health disorder, and as noted earlier, across all linguistic groups there was a nonsignificant trend toward higher mistrust among those with mental health disorder.
A nonsignificant trend was seen toward lower prevalence of diabetes (0.96 [0.90, 1.01]).
APOE4 mice show a nonsignificant trend of shorter path lengths, however relative levels of reduction over the training days (i.e., learning) trend in favor of APOE3 mice (control: 20.4% ± 9.1, 17αE2: 17.4% ± 7.7 reductions) versus APOE4 mice (control: 10.3% ± 6.5, 17αE2: 5.2%± 3.7 reductions).
latifolia shows a nonsignificant trend to decrease.
However, in the “hard” naming condition, adults also showed significant decreased activation over the right supramarginal gyrus relative to the easier conditions, and a nonsignificant trend for less activation in the left homolog.
In females and males, adherence to dietary seafood recommendations by them individually or jointly was not significantly associated with fecundability or subfertility risk, although a nonsignificant trend toward an association with higher fecundability and a lower subfertility risk with both partners adhering to the dietary seafood recommendation, as compared with neither partner adhering, was present ( FIGURE 1 , FIGURE 2 ).
Similarly, there was a nonsignificant trend from the second to fourth quartile in terms of increasing odds for low GS [Q2: OR 1.72 (95% CI 0.31, 1.69); Q3: OR 1.14 (95% CI 1.54, 2.52),; Q4: OR 1.48 (0.73, 2.99)] compared to the first SAF quartile.