As expected, preablation tissue samples with higher grades of dysplastic BE and EAC had significantly more TP53 and APC mutations and tumor suppressor gene mutations overall, as well as a nonsignificant trend for more chromosomal arm level CNVs and oncogene amplifications (Table 1 ).
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Estimated mean eGFR values at year 10 were identical for the monthly versus bimonthly belatacept maintenance groups (and significantly better than groups treated with cyclosporine-based immunosuppression), even though there was a nonsignificant trend toward increased rates of biopsy-proven rejection with patients administered belatacept only every 8 weeks. 25 However, all these rejections occurred early (within the first year) and it was unclear if the heightened risk of rejection could really be attributed to the interval of belatacept administration due to the double randomization trial design and lack of sufficient power.
[ 12 ] Although hilar obstruction showed a nonsignificant trend toward infection risk in our multivariate model, this finding aligns with pathophysiological mechanisms of bile colonization in proximal obstructions.
In contrast, RhoA activity showed a nonsignificant trend toward elevation following STEMI stimulation (Fig. 4 J).
There was a nonsignificant trend toward a lower [Na]s48 correction in the prophylactic group compared with the reactive group.
The two studies noted a nonsignificant trend towards lower recurrence rates and death from patients with macroscopic sentinel node metastasis.
There was a nonsignificant trend for increasing environmental variance after ChronAge 75.
Intriguingly, a meta-analysis conducted by Zeng and colleagues [ 24 ] showed a nonsignificant trend of 19G needles pertinent to sampling capability in relation to 22G counterparts.
42 months: HR, 0.76; 95% CI, 0.63 to 0.91), with a nonsignificant trend toward improvement in those with tumor expression of PD-L1 ≥50% (median DFS not reached in either arm: HR, 0.82; 95% CI, 0.57 to 1.18).
The effect on the nuclear shape was not so pronounced, and we found only a nonsignificant trend for lowering the mean NSI (0.81 versus 0.86) and the change in NAR from 1.68 versus 1.34 for ADMSC adhering to native vs. oxidized collagen, respectively. 2.3.
29 There was a nonsignificant trend to more frequent toxicity-related drug discontinuations among the octogenarians (9% vs 7%).
There was a nonsignificant trend for improvement of hemodynamic status as shown by increased mean arterial pressure (MAP), decreased norepinephrine dose, inotropic score, and vasopressor dependency index.
T-pulses also have long-term effects on call production in California mice, such that days after multiple T-pulse injections in the field, males produced more call types with a nonsignificant trend to produce more ultrasonic vocalizations (USVs) ( Timonin et al., 2018 ).
(2010) found a significant decrease in Glu/Cr over time in the acamprosate group and a nonsignificant trend of an increase in Glu/Cr in the placebo group.
After treatment, liver zinc concentrations had a nonsignificant trend toward a milling effect and were not affected by the VA source or a VA source-by-milling interaction.
Only a nonsignificant trend toward more depolarized RMPs was detected with CASPR2 antibody.
However, our SW620 cellular model endogenously expresses low levels of PD-L1 mRNA, and without induction, we observed only a nonsignificant trend indicating the downregulation of PD-L1 in KOAGR2 cells.
There was a nonsignificant trend suggesting that male grooming of female mating partners differed among pre-mating season, mating season, and post-mating season (H2P3) (Friedman tests: number of grooming bouts: χ 2 = 4.923, n = 7, df = 2, p = 0.085; duration of grooming: χ 2 = 4.923, n = 7, df = 2, p = 0.085).
Mean high-density lipoprotein cholesterol showed a nonsignificant trend toward lower levels in the Singapore discovery cohort.
The SEM for GD showed that functional groups asynchrony at GD was positively correlated with GST and NGST, but negatively correlated with GSP, and the positive effect may have offset the negative effect to some extent, leading to a nonsignificant trend of functional groups asynchrony.
The serum ALT levels in lean hamsters did not rise over the course of infection, whereas a nonsignificant trend towards elevated serum ALT levels was observed on dpi 4 and 7 in obese NASH hamsters, which was suggestive of greater liver damage during SARS-CoV-2 infection.
Similarly, the analysis of major bleeding in this subgroup showed a nonsignificant trend toward increased risk (RR: 1.92, 95% CI: 0.01–470.93), though with substantial uncertainty in the estimate.
Interestingly, there was a nonsignificant trend towards a longer duration of response for Faslodex (median 19.3 versus 10.5 months), and an additional 24.8 and 18.6% of patients, respectively, had stable disease for 6 months.
Authors found that at 1 h PI both the 55 Co- and 64 Cu-labeled agents showed a nonsignificant trend towards higher uptake than [ 68 Ga]Ga-DOTATATE.
Interestingly, many patients showed a nonsignificant trend toward improvement in function rather than loss at 2 y after biopsy.