OCT2 was expressed in a much smaller proportion of tumours (5; 14%), all of which were either positive for SSX2-4 and SAGE1 or negative for both markers ( Figure 3B ); there was a negative trend between OCT2 and SSX2-4 expression, although this did not achieve formal statistical significance ( p = 0.08, Fisher's exact test).
Additionally, there was a negative trend toward non-significance with the increasing number of missing values in all methods, excluding the SFI-hybrid ( Figure S2 ).
Regarding the Covid-19 pandemic in Germany, the association between the pandemic and social participation outcomes at follow-up was visualized, showing a negative trend (Fig. 2 , Panel A).
Furthermore, while sexual desire/sexual arousal was not significantly associated with subsequent physical fatigue, the association shows a positive trend in women and a negative trend in men, thereby potentially explaining the insignificant result of the overall association.
In contrast, eGFR, DBP, and the usage of calcium and vitamin D showed a negative trend toward a longer duration of diabetes (Table 3 ).
No effect for interval was found (for G inact : p = .225, for G act : p = .647), although G inact showed a negative trend of perceived motivational state over time, falling to 28% lower at intervals 5 and 6.
Similarly, GLUT3 is positively correlated with circadian changes in blood glucose in young adult rats while associations in aged rats exhibit a negative trend.
Notably, there is a significant positive trend of up to 0.15% per year (under SSP126) and a negative trend of up to − 0.35% per year (under SSP585) for TN10p, as illustrated in Fig.
In the absence of validated predictive indices of therapeutic response to rescue therapies, one should proceed to colectomy if there is a negative trend in: clinical indices (comprised of vital signs, rectal bleeding and abdominal tenderness), biomarkers (rising CRP), colonic dilatation on abdominal imaging or endoscopic deterioration.
Further, although not significant, a negative trend between thyroxine levels and PSS scores could be observed.
less than 0.93, rat eradication is not sufficient to reverse a negative trend of the population growth rate.
When comparing the four severity classes, we observed a negative trend in testosterone levels in correlation with disease severity, while in comparing the “severe/critical” and “mild/moderate” groups, the testosterone levels in the former were significantly lower.
have shown how add-on D-cycloserine to typical (haloperidol) and atypical (clozapine) antipsychotic treatment, modulate the expression of Homer 1a, in a negative trend in caudate-putamen ( 187 ).
In this sense, some of the twelve studies did not find associations between leptin and IgE in both teenagers and adults [ 68 , 82 ], which suggests that the role of leptin in AD pathogenesis may be due to other inflammatory mechanisms not mediated by IgE, or reported a negative trend in children, thus suggesting that leptin is associated with intrinsic AD [ 81 ].
We also defined a positive trend as a value of variation greater than zero and a negative trend as a value of variation lower than zero.
The MN-MNP nanocarrier showed a negative trend in IL-6 expression.
On the contrary, merino breeds had an average N e > 150 and an expected increase in inbreeding <5% within 50 years, but a negative trend for population sizes and number of effective sires.
The Bland-Altman plot in the CV showed a negative trend, with the mean of the first and second assessments being larger, while those in the other parameters showed no trends.
Quantitative Outcomes Reported quality of life (QoL) among the PLWD showed a negative trend throughout the study, though this decline was less steep during the intervention period.
For all regions dominated by long-term TWS depletion, only eastern Brazil (region 6) is collocated with strong nonstationarity in GPP, dominated by a negative trend, reflecting the combined impacts of deforestation, agricultural intensification, and an extended drought ( 35 , 36 , 47 ).
All three instruments showed a negative trend with deteriorating VA, although EQ-5D and 15D showed better sensitivity than EUROHIS-QOL8.
Although a negative trend was seen between most gestational ages and the type of care, this association was less strong.
As maize showed a negative trend, in relative terms, reaching a relative value of 0.52 by the end of the period, ecoefficiency of the soybean crop remarkably increased, showing a relative final value of 7.22 in 2019 ( Fig 6 ).
A negative trend in vital signs may indicate clinical deterioration [ 6 ].
The bias value shows a negative trend at all illumination levels and an increase, especially at high levels.