“a negative trend”

On the other hand, the intrasession CV had a negative trend with time ( P = 0.001; 95% Cl, –2.256 to –0.549), indicating greater intrasession repeatability of the measurements as the screws remained in place longer.

One study found a negative trend in calcium intake across quintiles of free sugar intake in participants aged 4–10 years ( p < 0.001) and 11–18 years ( p < 0.01) [ 19 ], and another reported a negative trend across six free sugar cut-off levels ( p < 0.001) [ 38 ].

There is also a negative trend in the transition from Ebola to post-Ebola for maternal admissions (−7, 95% CI −10 to −4, p<0.001), MDOCs (−4, 95% CI −7 to −1, p=0.009) and institutional deliveries (−3, 95% CI −5 to −1, p=0.001).

The effect of number of repetitions differed between the series, with a negative trend in the first series and a neutral slope in the second and third series (main effect for repetition number: OR = 0.98, 95% CI [0.96, 0.99], p < 0.001; interaction between second series and repetition number: OR = 1.02, 95% CI [1.00, 1.04], p = 0.018; interaction between third series and repetition number: OR = 1.02, 95% CI [1.00, 1.04], p = 0.044).

Descriptive analyses showed a negative trend (JT test, p -value <0.001) between the share of total commuting time spent active and the commuting distance (Fig. 2 ).

Temporal analysis of genome size (2000–2025) revealed an overall positive correlation (ρ = 0.17, p < 0.001, n = 1,067), with complete genomes showing stronger correlation (ρ = 0.223, p < 0.001, n = 45) while contig-level assemblies exhibited a negative trend (ρ = −0.214, p < 0.001, n = 776), likely reflecting assembly fragmentation artifacts.

A negative trend of the ratio between quartiles 1 and 4 was observed: 3.36, 1.34, 0.68 and 0.38, respectively (p <0.001, Table 2 ).

Mean VAI in women with prior GDM was significantly higher than the non-GDM group (19.7, 95%CI: 6.24, 33.15, P = 0.004), although both groups overtime experienced a negative trend (− 10.9, 95%CI: -13.1, − 2.1, P < 0.001); the GDM group showed a higher decrease in VAI (mean changes: -6.62; 95% CI, − 11,-2.1; P interaction = 0.001).

A negative trend could be noted between the general frequency of use and the respondents’ gender (p < 0.001).

Long‐term changes in growth rates at the population level When examining the long‐term changes in growth rates per site, the Columbretes Islands presented a negative trend in linear extension ( r 2 = 0.717, p = 0.002) and calcification ( r 2 = 0.595, p = 0.009) between 2003 and 2012, and a positive trend in density ( r 2 = 0.635, p = 0.010) and calcification ( r 2 = 0.536, p = 0.025) between 2013 and 2021.

After introducing the strategy, these groups have a statistically significant decrease in CS rates, which reflects a negative trend (e.g., overall CS rate decreased post-intervention by −0.87% annually, (p = 0.002)).

Western blot analysis confirmed that ABHD6 protein levels were consistent across all samples, whereas gel‐based ABPP analysis revealed that ABHD6 activity was significantly lower in resilient individuals, with a negative trend in AD donors (Figure 4G‐I , Figure S4 : resilient vs control, p = 0.0023; AD vs control, p = 0.068, AD vs resilient, p = 0.089).

Finally, the correlation between Snail1 and PVT1 was obviously positive while the correlation between Snail1 and miR-325-3p was a negative trend according to Spearman correlation coefficient analysis ( Figure 4E , p = 0.0024).

For subclonal mutations, all our observations remained significant (anti-EGFR, β = 9.86, P = 6.23 × 10 −05 ; DNA repair, β = 11.41, P = 2.94 × 10 −06 ; length of time on cytotoxic agents, β = 0.28, P = 0.0027), and there was a negative trend for the time between samples ( β = −0.15, P = 0.0027).

In contrast, Streptococcus mutans (2 studies) and Lactobacillus salivarius (1 study) showed no significant difference, with the latter exhibiting a negative trend (SMD = −1.500, 95% CI: −2.504 to −0.496, P = .003).

In mothers with at least one HAWD and no AD use, there was a negative trend (p-value=0.003) over increasing SES.

Over the past 65 years, the B IM also showed a negative trend of −0.14 ± 0.04 GtC yr −1 per decade, statistically significant at the 1% level ( P = 0.003), with a positive B IM in the early part of the record and a negative B IM in the most recent years (Extended Data Fig. 1 ).

Amotivation (AM) showed a negative trend, with a change in AM of − 0.3 (0.7) p = 0.003.

In the short term, preterm birth had a negative trend (0.02 decrease, P = 0.003), and in the long term had a decrease trend about 0.001 ( P = 0.003).

There was an increasing trend in patients undergoing TAVR with obesity ( p = 0.016) and smoking ( p < 0.001), while a negative trend was observed in patients with peripheral vascular disease, the prevalence of which decreased from 32.5 to 19.8% ( p = 0.003).

In line with this, a correlation analysis between NO and AsPgb expression revealed a negative trend across the full time course ( r = −0.32); however, this became stronger at intermediate stress stages ( r = −0.40) and became highly significant at 40%–45% sRWC ( r = −0.98, p = 0.0032).

Serum zinc showed a negative trend with estimated GFR ( P = 0.004) and significant reduction in albuminuria, with stage A3 ( n = 29, 65.7 ± 13.9 μg/dL) having lower levels than A1 ( n = 131, 76.4 ± 14.1 μg/dL, P = 0.001) and A2 ( n = 67, 78.4 ± 13.1 μg/dL, P < 0.001).

The linear regression between Sexual Abuse scores and metabolite concentrations showed a negative trend for choline ( p = .004), and positive trends for cystathionine ( p = .008) and homogentisic acid ( p = .022).

Among the filled spots, the proportion of positions filled by US MDs has declined from 96.69% in 2008 to 84.69% in 2022, a negative trend that was statistically significant at P = 0.005 with a beta coefficient of − 0.008.

The linear regression model reveals a negative trend between the rating of the local health care waiting time and the choice to travel for care, operationalized as the odds of traveling [ F (1,3) = 68.45, p < 0.005] with an adjusted R 2 of 0.94.