“a negative trend”

Amplification of HER1 caused a negative trend for survival (HR = 1.24 (95% CI 0.77 to 2.00), p = 0.380), whereas HER4 resulted in a decrease in the HR (HR = 0.36 (95% CI 0.06 to 2.36), p = 0.289).

Conversely, Blys and IgG3 levels showed a negative trend, which was not statistically significant (p = 0.38).

Of note, we observed that delta CRP revealed even a negative trend with delta DAS28 ( p = 0.38, r = − 0.30) (Fig. 4 b) and delta miRNA-5196 ( p = 0.42, r = − 0.28) (Fig. 4 c).

Similarly, weight changes also exhibited a negative trend with ghrelin levels ( β = −0.40, 95% CI: −1.29–0.49, p = 0.380), but this association was not significant, with no explanatory power ( R 2 = 0.00%).

Serum Zn and biomarkers Serum Zn was not correlated with the LA/DGLA ratio in females and there was a negative trend in males (Spearman: r = − 0.05, p = 0.39; r = − 0.11, p = 0.07, respectively).

The proportion of naive T cells showed a negative trend association with the 17‐item Hamilton Depression Rating Scale (HAMD‐17, r = −0.22, p = 0.39) or 16‐item Quick Inventory of Depressive Symptomology–Self‐Report (QIDS, r = −0.37, p = 0.10) scores, which was not seen in GZMH + CD8 + Tm cells (Figure 2B–D,F–H ).

For state 3, the WAB‐AQ scores showed a negative trend with both FT ( r = −0.328, p = 0.393) and MDT ( r = −0.382, p = 0.225), but the correlation was not significant. 4 Discussion The present study employed the ICA‐based sliding window technique and k ‐means clustering method to investigate alterations in dFNC and the relationship between the temporal properties of dynamic networks in patients with PSA and language dysfunction.

Roxadustat showed a negative trend with a medium effect size (Cliff’s delta = -0.56, p = 0.400) and a mean difference of -0.34 (95% CI [-1.02 to 0.34]).

Effects of EMR on Monthly ALOS Like the pre-DPC/PDPS period, the pre-EMR period also saw a negative trend in monthly ALOS, except for the age group of 50–64 years ( p = 0.4084) ( Table 3 ).

The neck pain results showed a negative trend of having a lower index value for subjects reporting neck pain vs. patients without neck pain [ p = 0.440, A = 0.636, p(P < A) = 0.03].

Conversely, for participants with a family history of AD (FH+), there was a positive trend between vitamin B12 intake and connectivity in IC 8 (beta value = 0.0007; p = 0.4703), and a negative trend for IC 19 (beta value −0.0006; p = 0.4549), although these trends were not statistically significant.

In women, positive trends between the time elapsed since COVID-19 infection onset (less than 2 years) and physical health (Tau = 0.050, P = .51), mental health (0.044, P = .56), and reaction time (0.035, P = .63), with fatigue being significantly affected (Tau = 0.158, P = .039), and also a negative trend with error rates (Tau = −0.055, P = .46) were observed.

The model indicated a negative trend in AMH levels from the first to the fourth quartile, with a slope of −0.02 ( p = 0.467).

A negative trend between the appendicular skeletal muscle mass parameter (ASSM) and the expression of PTGER4 has been noted (r = −0.224, p = 0.484).

There was no statistically detectable relationship between time-attacking and egg mass ( P >0.40); however, the data followed a similar pattern, no relationship in 2009 and a negative trend in 2010 ( Figure 2 ), (2009: P >0.50; 2010: R 2 = 0.23, P = 0.1179).

A negative trend was observed between the ΔCarotids and the ΔBAT mean TBR max ( r = −0.239, P = 0.506) and between ΔVAT and ΔBAT mean TBR max ( r = −0.593, P = 0.071).

In addition, plasma CTHRC1 showed statistically significant positive correlation with RF (ρ = 0.596, p < 0.0001, Figure 5E and Table 1S ) and ACPA (ρ = 0.35, p = 0.008, Figure 5F and Table 1S ), but not with ESR, which exhibited a negative trend that did not reach statistical significance (ρ = −0.088, p = 0.512, Figure 5D ; Table 1S ).

Restricted cubic spline analysis revealed a positive linear relationship for the risk of limb ischemia (linear, P = 0.006; area under the receiver operating characteristic curve of 0.75 [95% CI, 0.656–0.848]), a U-shaped trend for bleeding events (nonlinear, P = 0.214), and a negative trend for thrombotic events (linear, P = 0.552).

The GEJC in females showed a negative trend (15.26 to 12.35, a 19% decrease over 30 years), with a − 0.08 ([95% CI: − 0.39 to 0.24], P = 0.596) per 1,000,000 person-years average annual decline (Table 1 and Supplementary Table 2 ).

In order to exclude the possibility that the NLR trend was due to a concurrent bacterial or fungal superinfection, we compared the rates of superinfections among patients who had a positive trend with those who had a negative trend and observed that the presence of a superinfection was not associated with a higher NLR trend at admission (χ 2 (1, N = 469) = 0.45, p = 0.6) ( Fig. 4 ).

Correlation of eGFR values with duration of lithium therapy by linear regression (controlling for age and gender) showed a negative trend which was not statistically significant (beta = -0.07, B = -0.16, p = 0.66).

MD10° showed a negative association with mT in POAG ( p < 0.001), a negative trend in PPG (0.078) but none with controls ( p = 0.69).

After controlling for STH egg density, a negative trend in association ( r = − 0.171, P = 0.784) was observed between S. haematobium egg density and malaria parasitaemia.

For human-generated summaries, general plausibility demonstrated a negative correlation ( r = −.91, P = .833), and linguistic style also showed a negative trend ( r = −.58, P = .979).

The results showed a negative trend, both in the frequency and deviation of the median values of all studied cardiometabolic risk factors.