“a marked trend”

However, the BoHV-4-M-NSP5 prime-boost vaccination showed a marked trend toward reduced lung pathology following PRRSV-1 challenge.

When comparing the first quartile of the CALLY index as a reference, an increment in each subsequent quartile of the CALLY index is significantly linked to a reduced odds ratio for CRS, demonstrating a marked trend ( p for trend <0.001).

From 1995 to 2015, few respondents introduced ultrasound per year; however, from 2016, there was a marked trend of a gradual increase and more than half of the respondents (58.5%) introduced ultrasound into their practice in 2022 and 2023 This trend aligns with the emergence of research on standardizing ultrasound use for critical acupuncture points, reported in Korea in 2017, [ 7 ] and a surge in the publication of case series/reports utilizing ultrasound-guidance from 2019.

[ 6 ] In 2018, a study conducted by the Ecuadorian Psoriasis Foundation determined that approximate 0.59% of the country’s population suffers from this condition, in addition to a marked trend toward an increase in cases; currently, there are approximately 100,000 Ecuadorians diagnosed with psoriasis, with a predilection for male patients, between 40 and 60 years of age.

A marked trend for higher OXT was observed in the three genotypes of CC, CT, and TT in ASD patients relative to control.

NFIX ex 7 missplicing was less distinct, but also here, a marked trend was observed between repeat length and exon inclusion levels.

The remaining 15 metabolites demonstrated a marked trend toward elevation in patients, with LysoPC(16:0/0:0), LysoPC(18:1/0:0), LysoPC(0:0/18:0), and LysoPC(20:4/0:0) decreasing in group Y.

In relation to circumferential residual stress in aorta artery ( Figure 6A ), which can be quantified by the ring opening angle results, there is a marked trend to decrease its value when the ANP and Cinaciguat treatments are applied, where this difference is noticeable marked in the PAA zone, with statistically significant differences in both treatments.

Regarding the impact of the HSu diet on the cardiac tissue, our results indicated that 9 weeks of treatment might be associated with initial cardiac changes, as suggested by the increased LV weight/BW ratio (P < 0.01) and a remarkable brain natriuretic peptide (BNP) mRNA overexpression (P < 0.01), together with a marked trend for an upregulation of other important mediators of fibrosis, hypertrophy, angiogenesis and endothelial lesions, as well as oxidative stress.

There was a marked trend for isolated patients to exhibit higher levels of depression, the pooled standardised mean difference being 1.28 (95% CI 0.47 to 2.09) and anxiety 1.45 (95% CI 0.56 to 2.34), although both had high levels of heterogeneity, and worse outcomes for a range of care-related factors but with significant variation.

Previous reports from Sub-Saharan Africa [17] , [18] found trends towards markedly lower levels of positive Quantiferon/QFT-IT but not T-SPOT.TB results in individuals with CD4+ T-cell counts of <100, whereas other studies from low TB prevalence countries had not seen such a marked trend [21] .

As the two competitors experienced increasing fitness inequality there was a marked trend towards greater dominance of the more fit competitor, especially for larger initial population sizes and in the model with high growth rates.

nasus , environmental deterioration and long-term captivity have led to severe degradation of genetic quality, evident premature ovarian maturation, and a marked trend towards population miniaturization.

Worldwide, starting from the early 1980s, there has been a marked trend of changing from elite to mass higher education ( Chen, 2008 ).

However, also in the other parameters, there was a marked trend toward reduction.

At the start of the stroke there was a marked trend of reduced anterior pelvic rotation associated with increased lumbar flexion as the rating increased this was marked during final maximal effort test.

Both chronological and maturational analysis showed a marked trend to detect larger asymmetries before and during PHV (U12 and U14 groups when considered chronologically).

In terms of mass, the mean weight of tumors in mice receiving 5 mg/kg fucoidan was 137 ± 19.0 mg and 89 ± 33.0 mg in those receiving 10 mg/kg; there was a marked trend of decreased tumor weight compared with the control group, in which tumors were 397 ± 15.4 mg ( Figure 5 B).

found that the western part of North China Plain, Loess Plateau, Sichuan Basin and Yunnan-Guizhou Plateau had a marked trend of drying from 1961 to 2012 39 .

6–8 Social, environmental and biological factors are likely to contribute to such a marked trend. 9 PA is an overarching term that consists of many structured and unstructured forms within school and out-of-school-time contexts, including organised sport, physical education, outdoor recreation, motor skill development programmes and active transportation such as biking and walking.

3 b) followed a general pattern similar to that of IgA, with the exception of the response elicited by the group immunized in alum by intramuscular route, which showed a marked trend to develop a higher reaction.

[ 30 ] There was a marked trend toward improvement in patient satisfaction with care following psycho-cardiology interventions, emphasizing the importance of thoroughly informing both clinicians and patients about the advantages of psycho-cardiology care in patients undergoing AVS.

EST with PRP induced a marked trend to less deep thermal injury in both studies.

We observed a marked trend toward an increase in mid‐systolic notch (Fig. 4 E) and increases in systolic RV pressure (data not shown).

Introduction Closed reduction (CR) is one of the most common procedures for treating late-detected developmental dislocation of the hips (DDH) ( 1 ), considering a marked trend toward spontaneous improvement of the hips after reduction ( 2 - 4 ).