“a favorable trend”

Our results demonstrated significant improvements in PFS and ORR with combination therapy and suggest a favorable trend in OS in HBV-related HCC.

Notably, the pregnancy outcomes showed a favorable trend in the early hysteroscopy group, but there were no statistically significant differences.

With the availability of intermediate and long-term preservative media, and implementation of a cornea distribution system since 2012, the distribution of donor corneas has seen a favorable trend nationwide and there has been an increase in cornea collection/utilization at several eye banks when compared to earlier years.[ 15 ] However, there still exists a huge gap in the demand and supply of donor corneas in several parts of the country.

162 , 172 , 173 In conclusion, Impella as mechanical support in high-risk PCI is backed by evidence that is not always consistent but shows a favorable trend for better short- and long-term outcomes compared to unprotected procedures or those performed with the assistance of other devices.

43 Nonetheless, the results indicate a favorable trend toward improved recovery in the lidocaine group.

These subgroup-specific analyses support a favorable trend in biomarker responses for the PL omega-3 formulation, particularly in individuals with elevated baseline TG or lower initial O3I.

In this study, although not statistically significant, the 30-day mortality rate in the emergent group (0%) was lower than that in the non-emergent group (25.0%), suggesting a favorable trend toward improved early outcomes with earlier intervention.

Concurrently, aortic atherosclerotic area, lipid levels, liver oxidative stress, and body inflammation were improved, showing a favorable trend of change.

A favorable trend toward improvement in median progression-free survival (6.0 months versus 4.1 months) and overall survival (13.0 months versus 9.7 months) was also observed in the vorinostat arm.

Responses of moderate intensity enhanced the outcomes and high-intensity shows a favorable trend with limited data.

Interestingly, reduced doses were associated with a significant reduction in incidental or asymptomatic VTE, and a favorable trend was observed in composite bleeding outcomes, including a statistically significant reduction in combined major and CRNMB events.

Overall, SGLT2i showed a superior profile in terms of anthropometric outcomes and liver enzyme improvement, with a favorable trend across most markers, particularly in the placebo subgroup, reinforcing their potential role in metabolic dysfunction-associated conditions like MASLD/NASH.

Conclusions The K-Hammer technique improves operative efficiency, reduces pin insertion attempts, and demonstrates a favorable trend toward reduction in iatrogenic ulnar nerve injury risk (ARR 11.9%, NNT = 8.4), without compromising radiographic or functional outcomes.

CRT, including volume-based brachytherapy, followed by pembrolizumab demonstrated a statistically significant and clinically meaningful improvement in progression-free survival, along with a favorable trend in overall survival, in patients with locally advanced high-risk cervical cancer.

Even though a favorable trend was seen towards ARS[ 11 , 12 , 15 ] in improving gastroesophageal reflux and dysphagia score, pooled statistical analysis did not show significant difference between those two stents.

KBD3536 also showed a favorable trend compared with orlistat.

In the subgroup analysis for OS, including propensity score‐adjustment and propensity score‐matching analysis, regorafenib was a favorable trend of OS in the younger patients, whereas TFTD was in the elderly patients.

For example, the KEYNOTE-061 trial, which evaluated pembrolizumab monotherapy versus paclitaxel in previously treated gastric cancer, failed to demonstrate a significant improvement in PFS or ORR, despite showing a favorable trend in OS among patients with high PD-L1 expression (CPS ≥10) ( 30 ).

In the third ΔTG tertile, fenofibrate treatment showed a favorable trend toward lower all-cause mortality among early-diagnosed patients, with a significant age-by-treatment interaction (P interaction = 0.012), whereas no benefit was observed among late-diagnosed patients.

ET-calculated maximal pre-treatment k ep showed 100% sensitivity and specificity for predicting treatment response during the early phase of the therapy and reached a favorable trend to significant prognostic value post-therapy.

These findings suggest a favorable trend, but definitive cardiovascular benefit cannot be concluded until results from dedicated CVOTs, such as SURPASS-CVOT, become available.

Detecting the changes in the levels of urinary THP and PTX3 of each group, it was found that urinary PTX3 levels of CLAT and TLF groups were lower than pretreatment, whereas urinary THP levels in the CLAT group did not show a favorable trend post-treatment. urinary THP levels reflect kidney functioning mass and are of prognostic value for renal function.

The current results suggested that MHO showed a favorable trend in the overall metabolic signature.

The GOURMET-HF trial [ 142 ], including both HFrEF and HFpEF patients, demonstrated that the Dietary Approach to Stop Hypertension (DASH)/sodium-restricted (SDR) diet has a favorable trend in rehospitalization at 30 days.

However some RCTs detected a favorable trend towards 20-30% relative risk reduction mortality in certain patient subsets.