Though larazotide acetate could not demonstrate a statistically significant efficacy in the reduction of intestinal permeability, a favorable trend was seen[ 82 ].
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“a favorable trend”
Sighted at
p=0.09
In the literature
(One woman was taking a statin at baseline but not at 3 and 6 years, and another woman was under statin treatment at the 3- and 6-year follow-up visits.) Except for glucose, which showed an increasing trend possibly reflecting an underlying propension of PWS, the mean values of the remaining laboratory markers showed a favorable trend, i.e., increase of HDL cholesterol, decrease in triglycerides, and decrease in systolic and diastolic blood pressure.
Although not statistically significant, this finding suggests a favorable trend regarding the intervention’s effectiveness.
Though the outcome showed a favorable trend but did not reach statistical significance.
In a study conducted by Dueñas et al, 14 6 months after infarction, males exhibited a favorable trend for improvement, especially in most domains constituting the overall assessment of physical health in the 36-Item Short Form Health Survey questionnaire, while females exhibited improvement only in the Physical Component Summary and social functioning domains.
Ankle dorsi-flexor strength improvement was significantly greater in the medium-frequency group (1.93 ± 0.25 grade) compared to both low (0.97 ± 0.18 grade) and high-frequency groups (1.03 ± 0.18 grade) ( p < 0.001), with a favorable trend also observed in FAC.
Although anti-EGFR therapy in the first-line setting has a favorable trend compared with anti-VEGF therapy, the treatment strategy in RAS wild type mCRC has been controversial.
While high blood levels of 25(OH)D have been shown to reduce lung cancer mortality, with the link between lung cancer patients' serum 25(OH)D levels and survival rates showing a favorable trend, 135 a meta‐analysis published in 2018 found no discernible dose–response connection between serum 25(OH)D levels and lung cancer risk.
Treatment with elafibranor 120 mg/day showed a favorable trend toward MASH resolution without worsening fibrosis, as confirmed by liver biopsy, while also improving lipid profile, insulin sensitivity, liver enzymes, and inflammatory markers [ 135 ].
Conclusions In this retrospective study of patients with nonparoxysmal AF after catheter ablation, dronedarone and amiodarone showed a favorable trend toward lower rates of overall early recurrence compared to propafenone.
Ordinal logistic regression confirmed significant improvement with laser therapy per dermatologist ratings (odds ratio = 2.10, P = .019), with a favorable trend observed for fat grafting.
To gain deeper insights, we integrated machine learning-assisted clustering with MD simulations, revealing a favorable trend in binding free energy (Δ G b ), suggesting enhanced complex stability.
In the subgroup analysis by country, both Chinese and non-Chinese studies showed a favorable trend for higher PNI, and no significant subgroup difference was detected (P=0.59).
We found modest differences in timing of outcomes among patients monitored with real‐time results (non‐Holter), compared with those using traditional Holter test—in general and contrary to expected, real‐time ambulatory monitoring patients did not undergo cardiac procedures sooner and did not present to emergency department or hospitalization sooner, though there was a favorable trend toward earlier initiation of oral anticoagulation among patients with real‐time monitoring.
The TUG test, assessing functional mobility and balance [ 45 ], showed a favorable trend for the exoskeleton group, suggesting potential improvements in dynamic mobility, including standing and initiating walking.
( 2024 ) tested the Pinhole Surgical Technique associated with A‐PRF versus collagen membrane, reporting similar results in pain (NRS), KTW, and GT at 3 months, with a favorable trend toward PRF.
In contrast, intranasal cooling was proved to be able to allow for the rapid achievement of the target temperature (34 °C) compared to other methods, 53 and a sub-analysis of the Princess trial 54 showed a favorable trend after rapid intranasal cooling in the sub-population with a shockable presenting rhythm.
While the study did not meet the primary outcome of between group change in Kansas City Cardiomyopathy Questionnaire summary score, but participants assigned to the DASH diet demonstrated a favorable trend in rehospitalization at 30 days (11 vs. 27%) ( 113 ).
There was a statistical difference in conjunctival hyperemia favoring KPI-121, while ocular discomfort showed a favorable trend versus placebo but without a statistical difference.
Updated data from this trial demonstrated a favorable trend in overall survival and response even within the pMMR subgroup, although statistical significance was not reached [ 14 ].
Although reductions in TNF-α showed a favorable trend, inflammation did not independently predict CAP improvement in this model.
The pooled HRs of analysis of among women with either HER-2 positive or HER-2 negative status showed a favorable trend but no statistical difference between the 2 treatment arms.
The two most common MBS procedures [sleeve gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB)] have been extensively studied recently, showing a favorable trend towards decreased rates of short-term morbidity and mortality, including a decreased risk of deep vein thrombosis/pulmonary embolism (DVT/PE), staple line or anastomotic leak, surgical site infection, and the need for reoperation [ 17 , 18 ], all of which were more significant in the past.
Return to normal activities showed a favorable trend in late TAPP cases (5.3 ± 0.5 days) compared to early cases (5.7 ± 0.5 days), although this was not statistically significant ( p = 0.103).
A log-rank test indicated a borderline statistical significance (p=0.058) in the survival distributions among the various DDD adherence levels, with a favorable trend in the lower dose group.