“a decreasing trend”

The genotype detection rates of 2v, 4v and 9v showed a decreasing trend with ages (all P < 0.05).

4 B left, * P < 0.05); in addition, the tumor volume showed a decreasing trend (Fig. 4 B middle, * P < 0.05), and the body weights of the mice did not appear in the BIRT377 treated group ( n = 13) than the control group ( n = 10; Fig. 4 B, right).

For interpreting the results, the following criteria were considered: an increasing trend - APC positive and p<0.05; a decreasing trend - APC negative and p<0.05; stationary, when the null hypothesis that there is no significant difference between the value of the variation and zero is accepted (p>0.05) ( 12 ) .

Neutrophil infiltration, visualized using the Tg (mpx: mcherry) transgenic line, was also increased in the stress model, followed by a decreasing trend upon probiotic administration (4.56 ± 2.43 in control group; 6.95 ± 2.48 in light-stress group; 6.19 ± 3.01 in light-stress/ B. longum group, p < 0.05) ( Figure 3 B,D,F,H).

The abundance of NDP52 protein decreased significantly in model mice compared with that in the controls ( P < 0.01), and the level of OPTN protein exhibited a decreasing trend ( P > 0.05); however, treatment with high- and low-dose PNS induced a significant elevation in the levels of NDP52 and OPTN proteins ( P < 0.05) (Fig. 4 E-I).

Prevalence of diseases A total of 3,493 chronic diseases were recorded in the population, corresponding to 4.6 diseases per LLI (4.8 in men and 4.5 in women, p < 0.05); there was a decreasing trend with age, from 4.7 in those under 98 vs. 3.3 in those over 100 ( p < 0.05).

These two alpha diversity indexes showed a decreasing trend in a stepwise manner from S, CS, and L to R (Dunnett's test, p < 0.05) (Figure 1A ).

While the proportion of CD31-positive cells showed a decreasing trend ( P > 0.05) (Fig. 5 Ac, f, i, D).

After being treated with ultrasound, the soluble protein content of the hybrid gels presented a decreasing trend ( P < 0.05).

3 B), leading to two periods with distinct trends: a decreasing trend between 2009 and 2016 [− 11.46% annual percentage change (APC), P < 0.05], where the proportion of patients with this CD4 + count decreased from 74.29% in 2009 to 35% in 2016 (Fig. 2 ), and an increasing trend between 2016 and 2019 (6.28% APC, nonsignificant), where the proportion of patients with this CD4 + count increased from 35% in 2016 to 36.84% in 2019.

10 μg/ml and 100 μg/ml HDM significantly decreased barrier resistance as measured already 1 h after exposure ( Figure 2B ), and a decreasing trend ( p = 0.0503) was observed using 25 μg/ml HDM.

IOP did not demonstrate an early postoperative increase and showed a decreasing trend as early as week 1 (median 13.0 mmHg [10.0–16.0]; p = 0.0509).

In atrophied muscle, the MEF2C mRNA level was profoundly decreased (−58%; p < 0.0001) together with a decreasing trend in the MYH7 mRNA level (−36%; p = 0.051) ( Figure 6 B–E).

There was no significant change in the length of a gait cycle, although there was a decreasing trend after the intervention ( Figure 2 b; pre, 1.31 ± 0.32 s; post, 1.25 ± 0.29 s, p = 0.051, Z = 2.90, r = 0.52).

In subgroup analysis for NSBB responders, LPS, LBP, and IL-6 significantly decreased (LPS, p=0.008; LBP, p=0.008; IL-6, p=0.008), and TNF-α also showed a decreasing trend after treatment (p=0.051) in the combination therapy group ( Table 4 ).

Low-protein diets had no significant effect on L*, a*, b*, or pH values between groups, but b 24h * had a decreasing trend ( p = 0.051). 3.4.

The HIV prevalence did not show a decreasing trend (trend test, p = 0.051).

The results showed that Shh expression at MDS was not significantly reduced compared with EDS ( Figure 1 P), whereas Fgf8 showed a decreasing trend ( p = 0.051) ( Figure 1 Q).

Post-hoc analyses revealed that PwMS in ROB showed a decreasing trend in path length between PRE and FU ( p = 0.051; see Fig. 3 for a statokinesiogram of sway path from two representative PwMS), while trunk variability significantly decreased between PRE and FU ( p = 0.030).

Of the tested parameters in the open field (total walking distance, total movement time, mean velocity, and mean angular velocity), the mean angular velocity was increased ( p < 0.001), and the total movement time showed a decreasing trend ( p = 0.051) for all treatment groups over time during the exercise regimen (i.e., main effect of “week”).

43.5% in 2002 and 2012, respectively; P = 0.645), whereas the annual proportion of neonatal complications overall showed a decreasing trend (from 38.0% in 2002 to 33.5% in 2012; P = 0.051).

The effect of Tai Chi on improving subjective sleep quality in older adults This study confirmed through PSQI and sleep diaries that 12-week Tai Chi intervention can significantly improve the subjective sleep quality of older adults, characterized by improved sleep quality, and the number of nocturnal awakenings showed a decreasing trend without statistical significance ( P = 0.051), which is consistent with the results of several studies ( Chen et al., 2025b ; Siu et al., 2021 ; Li et al., 2020 ).

Moreover, Gln-D, GLU-D, or SR had no effect on transcript levels of the anti-inflammatory factor IL-10 at three time points ( p > 0.05), but a decreasing trend was found at 24 h ( p = 0.051).

A decreasing trend ( p = 0.051) during COVID-19 pandemic (median = 495, range = 42, 3000) as compared to the pre-pandemic period (median = 825 euros, range = 90, 7320) was observed.

Interestingly, the reduction in the B cell response was restricted mostly to the spike S1 + S2 proteins ( P = 0.0012), while for the NC protein only a decreasing trend was observed ( P = 0.0515) ( Figure 2B ).