During 2016–2019, already a decreasing trend in SSI incidence after colorectal surgeries was observed (7.2%; 7.2%; 6.3%; 5.0%, respectively), while the proportion of closed procedures increased ( p < 0.01, Additional file 1 : Figure S2).
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Results Binocular choroidal thickness exhibited a decreasing trend from temporal to nasal regions, with slight thickening in the subfoveal region compared to choroidal thickness at T0.5 and N0.5 in both groups ( P < 0.01).
Comparison of the evaluations at 10 and 60 min after treatment showed a decreasing trend in ATP concentration in controls and treated independently of the stimulating or inhibiting effect ( p < 0.01– p < 0.001). 3.2.
The results showed that, compared with the LPS + sh-PTEN group, the LPS + sh-PTEN+Rapa group had significantly decreased SOD levels and significantly increased MDA levels ( P < 0.01), while the LPS + sh-PTEN + 3-MA group showed an increasing trend in SOD levels and a decreasing trend in MDA levels ( P < 0.01, Fig. 5 E).
The mRNA expressions of E2F and ESR1 were positively associated with FOXM1 , significantly increasing from LPAs to SPAs (Jonckheere-Terpstra test, P<0.01 Figure 2H,I ), while FOXO3A showed a decreasing trend (Jonckheere-Terpstra test, P<0.01, Figure 2J ).
A decreasing trend was observed for keratoleukoma ( P < 0.01) and an increasing trend for corneal endothelial dysfunction ( P < 0.01), regraft ( P = 0.012), corneal limbal dermoids ( P < 0.01) and congenital corneal opacity ( P < 0.01).
In this subgroup, mean plasma indoxyl sulfate concentrations demonstrated a decreasing trend from the baseline value of 2.5 ± 0.7 μg/mL, with values of 2.1 ± 0.9 μg/mL at week 4 (p < 0.01), 2.1 ± 1.3 μg/mL at week 12 (p = 0.07), and 2.0 ± 1.1 μg/mL at week 24 (p < 0.05).
From 2010 to 2019, the total age-standardized incidence rate (ASR) of LC showed a decreasing trend, from 50.91/ 100000 in 2010 to 40.45/ 100000 in 2019 (APC= -1.5%, 95% CI: -2.7–0.3, p<0.01).
Moreover, an immunofluorescence staining assay revealed a decreasing trend in the proportion of slow myofibers and an increase in fast myofibers in mice treated with BBE ( p < 0.01 for BBE50 and BBE100 in slow and fast myofibers) ( Figure 4 E,F).
Conversely, the protein levels of NLRP3 were elevated in the mod group compared to the sham group ( P < 0.01) and downregulated in the Brt-L, Brt-M, and Brt-H groups in a decreasing trend compared to the mod group (Fig. 4 E, P < 0.01).
The log-rank trend test indicated that there is a decreasing trend on the rate of 24-h mortality from WBR1 to WBR4 ( P < 0.01).
Conversely, SP-A exhibited a decreasing trend in the control and 0 h groups but increased in the serum of 24 h group ( F = 52.629, P < 0.01).
Blood biochemical parameters ( Table 4 ) indicated a decreasing trend in BUN concentration with increasing levels of MP supplementation in broilers (P < 0.01).
The rate of O 2 · − in oat seeds showed a decreasing trend throughout the aging process, with a highly significant difference observed between the two varieties ( P < 0.01).
After 5 days of PCP and PCP-1 administration, the mRNA content of age-1 and daf-2 genes in the nematodes of both the PCP and PCP-1 groups showed a decreasing trend compared with the control group ( p < 0.01).
Our data showed a decreasing trend in the mRNA and protein levels of DUSP22 after HUVECs had undergone EndMT ( P < 0.01) (Figures 1(a) – 1(c) ).
For MMT clinics receiving PMES only, before the intervention, there was a decreasing trend in the monthly average number of daily participants in every scale of the MMT clinics, with a baseline slope ranging from − 0.23 to − 1.98 ( p < 0.01 for all).
In particular, the frequency of LBW-PTB shows a decreasing trend (i.e., less frequent births compared with the average number of births per day) for weekends (p < 0.01), Holiday (p < 0.01), and Long Holiday (p < 0.01).
Both single infection and multiple infection exhibited a decreasing trend, with the AAPC for multiple infections (AAPC = −13.9%, p = .010) being higher than that for single infections (AAPC = −8.1%, p = .029) ( Figure 3 ).
The EFS and OS for patients with stage I, II, III, and IV MGCTs showed a decreasing trend, with EFS rates of 95.27%, 93.06%, 73.63%, 70.43% ( p < 0.01) and OS rates of 100%, 93.31%, 87.69%, 84.64% ( p = 0.04), respectively.
Table 5 shows that there was a highly significant difference in the test results of the TCE + RTG before and after the intervention ( P < .01), the data of the WG improved but not significantly ( P > .05), and the results of the CG showed a decreasing trend.
There was a slight increasing tendency in DDDc of Dasatinib in tertiary hospitals ( p < 0.01), and a decreasing trend in DDDc of Nilotinib in primary hospitals ( p < 0.01).
From December 2020 to August 2021, there was again a decreasing trend (MPC, -13.8; 95% CI: -23.3, -3.5; P = 0.01), followed by a slight increase from August 2021 to April 2022 (MPC, 4.2; 95% CI: -8.4, 18.6; P = 0.52).
There were more boy cases than girl cases every year, and the prevalence rate ratios ranged from 1.26 to 1.39 ( p < 0.05 in all years), with a decreasing trend over time ( p < 0.01).
There was an increasing trend of having missing teeth ( p = 0.03) as people aged and a decreasing trend in the number of filled teeth ( p < 0.01).