“a decreasing trend”

We observed a decreasing trend in both procedures during the study period ( P < 0.001).

The pH of the fish cakes was 7.09 in the control group and 6.87–7.04 in the garlic-powder groups, demonstrating a decreasing trend with increasing amounts of garlic powder (P < 0.001).

Despite the growth of CCBs, there was a decreasing trend of nifedipine utilization in prescriptions with antihypertensive agents from 18.9% (6,154/32,629) in 1997 to 6.4% (4,142/65,134) in 2011 ( p <0.001 in linear-by-linear association).

From 2006 through 2017, the proportion of cases of intentional injury showed a decreasing trend (z = 22.7, P < 0.001) (Figure 1 ).

There was a decreasing trend toward partial/total colectomies, rectosigmoid, and small bowel surgeries from 2009 to 2019 (p<0.001).

Among hospitalised patients, ICU-admissions were also different by season throughout the study period and showed a decreasing trend (p < 0.001).

coli isolates resistant to most of the antibiotic categories remained stable between 2015 and 2019, though a decreasing trend in the proportion of E. coli isolates resistant to fluoroquinolones (37.8–32.0%, p < 0.001) and aminoglycosides (15.6–11.9%, p = 0.002) was observed over time (Fig. 3 ).

Postoperative mPAP, which is measured when a BPA session is finished, also showed a decreasing trend (p<0.001); however, the improvement of mPAP in one session was quite small (1–2 mm Hg) compared with that in previous reports of mPAP in the follow-up period.

Each of the study outcomes had a decreasing trend across the study period (ordinary least square P -value <.001).

A measurement of the eradication rate using ITT and PP analyses from the years 1998 to 2013 showed a decreasing trend over this study period ( P <0.001, both).

While a significant decrease in EDV was not observed, there was a decreasing trend in both EDV and PSV with increasing effort (PSV: r 2 = 0.7477, p = 0.0013; EDV: r 2 = 0.3643, p = 0.0319; Figure S5 ).

The starch digestibility showed a decreasing trend with the increase in dietary amylose-amylopectin ratio ( R = −0.9893, p = 0.0013), and the values of fish fed diets 1–2 were significantly (p<0.05) higher than those of fish fed with other diets.

Treatment with GEO and citral caused a decreasing trend in plasma cholesterol and LDL-C levels in ApoE −/− mice compared with the GC group; moreover, high-dose GEO and citral increased plasma HDL-C levels ( p = 0.0015 and p = 0.0054, respectively).

PC exhibited a decreasing trend with an increase in the BMD quartile (Q1: 242.55 ± 56.12; Q2: 243.75 ± 58.61; Q3: 243.20 ± 58.40; Q4: 238.38 ± 56.79; P = 0.0017).

2 ) but remaining at the lower end of the overall copy numbers (0.05–0.2 copies/μl) and showing no significant pattern of eDNA signal accumulation over time except a decreasing trend for nylon, highly influenced by the high initial copy numbers ( p ≤ 0.0019, Fig. 3 ).

The mRNA expression of CYP27A1 and CYP27B1 were upregulated in the VDD group ( p < 0.001), VDR had a decreasing trend compared with the CON group in the brain; while the mRNA expression of CYP27A1 ( p = 0.002, p < 0.001) and CYP27B1 ( p = 0.008, p < 0.001) were downregulated, VDR ( p = 0.044, p = 0.010) was upregulated in the VDD + VD group and VDD + VD-FA/VB 12 group compared with the VDD group in the brain.

Before biosimilars were introduced, originator infliximab prices presented a decreasing trend in Australia ( P = 0.002), Canada ( P < 0.001), India ( P < 0.001), Japan ( P < 0.001), and Korea ( P < 0.001).

Trend analysis of the PM 10 dataset showed a decreasing trend (Modified M–K Hamed Rao approach test result: tau ( τ ) = − 0.3, p -value = 0.002) with a low rate of 0.2 μg m −3 per annum during 2018–2020 (Fig. 5 ).

During the study period, isocyanate-related asthma followed a decreasing trend ( P =0.002).

By day 60, ASV richness exhibited a decreasing trend with immigration in both homogenous treatments, reaching significance only in Long‐Long ( p = 0.002) but not in Fen‐Fen ( p = 0.151).

CK Total Activity In comparison with NHBx hearts, median total CK activity was significantly lower both in SevAS-rEF (by 43%, post hoc one-sided P =0.016) and SevAS-pEF (by 35%, post hoc one-sided P =0.028), resulting in a decreasing trend in median values ( P =0.002; Figure 4 A, Table 2 ).

The average consumption of ciprofloxacin showed a decreasing trend (−0.4 DDD per 1000 OBD per month, p = 0.002), while the average consumption of macrolide antibiotics, betalactamase stable penicillins, and piperacillin-tazobactam showed a slightly increasing trend ( Table 2 ).

Figure 1 (a) shows that there were no changes in overall adherence over time ( P = 0.108) and adherence in ED-PrEP users ( P = 0.270), whereas D-PrEP users showed a decreasing trend (from 78% in the first follow-up to 73.1% after 12 months, P = 0.002).

Change in Morphine Milligram Equivalents Prior to HB21, there was a decreasing trend in MMEs per day (rate of −.09 MMEs per study month, 95% CI −.16, −.04 MMEs per study month) ( P = .002) with a mean MMEs per day of 34.7 for all opioids during the study period; following implementation there was a non-significant increase in MMEs for all opioids to 37.4 (change of 2.69 MMEs, 95% CI −.51, 5.89 MMEs) ( P = .105) ( Table 1 ; Figure 2 ).

In contrast, MCDK shows a decreasing trend in Least Squares mean differences, with a significant negative difference at GA 32 ( p = 0.002), but no significant differences at 4 weeks postnatally ( p = 0.42) or at 2 years of age ( p = 0.88), suggesting that the impact diminishes over time.