“a clear trend”

ES for the number of fractures also demonstrated a clear trend of greater change with more fractures.

For formulations that had the same theoretical peptide-to-capreomycin ratio, their estimated ratio was not constant and did not show a clear trend as the total drug content increased, while doubling the peptide concentration in the formulation resulted in an increase in surface concentration of peptide.

The predictive ability in terms of correlations between genotypic values (used as phenotypes in the training process of GS prediction model) and predicted genomic breeding values showed a clear trend that reflected the heritability for each trait.

The investigational clinical pipeline, however, shows a clear trend toward the development of therapeutic antibodies that are more complex. 4–6 In addition to full-length canonical antibodies, the pipeline increasingly includes bi- or multispecific antibodies 7–10 and antibody-drug conjugates (ADCs), 11 as well as antibody fragments, fragment-Fc and appended Ig, which can be naked, conjugated to other molecules or fused to non-Ig proteins, and can have monospecific, bispecific, or multispecific properties.

In terms of MW, we observed a clear trend in researchers’ preference for low molecular weight chitosans—the dominant group consisted of chitosans with a molecular weight of below 30 kDa ( n = 39).

Reports of cases were initially concentrated in affluent areas but overall showed a clear trend with deprivation and risk ratio of 2·32 (95% CI 1·94–2·78) between the most deprived and the least deprived.

Collectively, these studies highlight a clear trend towards more intricate feature fusion and attention-based architectures.

A clear trend could also be observed in Fig 7 , namely that the OMU vectors of the drugs with negative GR max (negative growth) tended to have more OMUs correlated with negative mean GR max .

As expected, a clear trend towards accelerated migration was found for both inhibitors as compared to control treated cells, which reached statistical significance for WIN18.446 at 36 h (Additional file 5 : Figure S4C).

A clear trend of increasing elongation at break with mold temperature is observed, with stagnation at 60–70 °C.

We also found that the PVTTs until flowering (PVTT flowering ) of the new cultivars were 18% and 14% lower than the PVTT flowering of the old cultivars in the first and second years of the field experiment, respectively, whereas the differences in the PVTT flowering of the cultivars released before 1972 were small and did not show a clear trend (Fig. 2a,b ).

The data did not indicate a clear trend in infant gender sensitivity.

There was less of a clear trend in sample clustering in the PCA scores plot, and the larger number of bacterial genera in each sample may have contributed to this complexity (Additional file 8 : Figure S3).

We observe a clear trend: increasing the TPP concentration leads to a reduction in the required UV dose for initiating effective crosslinking.

Within coelurosaurs, and especially Maniraptoriformes, there is a clear trend for the expression of this feature [10] , [21] , [29] .

The results of the studies show a clear trend in which decisions to implement health information technology such as EMS are based on motivations other than the objectives of this research on effectiveness.

Although we did not observe a linear dose response, there was a clear trend for improved morbidities at the two lower doses.

Blood Pb concentration showed a trend to decrease with increasing distance from the smelter, but urinary Cd did not show a clear trend.

A clear trend was observed, where higher milling degrees resulted in a progressive reduction of all antioxidants due to the removal of the bran and germ layers, which are rich in these bioactive compounds.

A clear trend in the coalescence was observed, where shorter DHBCs exhibited more pronounced droplet fusion, which might be attributed to the steric bulk of the polymers.

Importantly, ga20ox1 ga20ox2 floral organ lengths across the early inflorescence under control growth conditions show a clear trend of increasing stamen and petal length with advancing flower position (Fig. 2 s, t).

However, the PPV and NPV values depict a different scenario, showing considerable variability across different experimental settings without presenting a clear trend of increase or decrease.

The effect of MMP-9 expression across migraine phases did not reach statistical significance ( F 3,22 = 2.81, P = 0.063), although there was a clear trend of a decrease in the preictal and postictal phases compared to the interictal and ictal phases (Fig. 2 C).

Slaughter age also affected meat lightness and yellowness, and a clear trend of darkening with age was observed across all groups, with yellowness increasing over time.

This represents a clear trend away from uncontained power morcellation since the 2014 FDA warnings.