Barely Significant
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“a clear trend”

19,461 sentences · 19,461 papers · 31,348 search hits before verification · confirmed specimen

Sighted at

p<0.09

Listed by Hankins (2013) · Otte et al. (2022)

In the literature

The MEP analysis confirmed the electronic transformation of the typically nucleophilic d 8 square-planar cores into strong electrophilic sites, demonstrating a “supramolecular Umpolung” where the metal center is switched from an electron donor to a π-hole electron acceptor. The MEP values showed a clear trend of decreasing electrophilicity among the divalent cations from Ni to Pt, which perfectly correlates with the increase in the experimental M···F distances and the corresponding weakening of the ion-pair binding energies.
One of the possibilities, continuity lesions are a plausible option, but directly in the available literature, it could not be verified as a clear trend of aggregation, so there remains uncertainty as to whether there is a pathophysiological mechanism that can explain it and for this reason, you should make the call to report more cases and be able to have a better idea of the associated causality.