“a clear trend”

Although both proteins were not significantly regulated compared to the other stimulation condition a clear trend was observed.

1 The United Nations Office on Drugs and Crime reported in 2019 a clear trend of “innovation” with the emergence of 892 new NPS between 2009 and 2018. 2 , 3 Legal control of NPS drugs differs from country to country.

However there is a clear trend towards lower numbers of immature NFIX derived colonies compared with MigR1 (CFU-E and CFU-GEMM) with a concomitant increase in more mature myeloid colonies (CFU-GM and CFU-G) ( Fig. 5A ).

Conclusion Although the available evidence is conflicting, there is a clear trend toward an association between female asthma and a reduction in fertility, and by that a larger proportion requiring fertility treatment, even though female asthma might not negatively affect total number of offspring.

There is a clear trend that surgeries with longer OR times have increased ergonomic risk.

Even though there was a clear trend between waist circumference and the detection rates of Methanobacteriales, the correlation coefficient of +0.23 between the number of Methanobacteriales and waist circumference can be interpreted as a weak association.

There was a clear trend of elevated clearance in the study populations.

Economic Aspects of Continuous Esterification The economic evaluation of continuous, membrane-based esterification processes reveals a clear trend toward superior profitability when compared to conventional batch operations.

Despite this, one can easily recognize a clear trend of high erectile dysfunction following salvage surgery treatments, with the erectile dysfunction rates at 1 year ranging from 45% to 100% [ 11 , 45 , 47 , 49 , 50 ].

While EOPC currently affects high-SDI countries the most, there is a clear trend over time showing a gradual shift of EOPC burden towards low-SDI countries.

In the MCMV-SIINFEKL group, we observed a clear trend in the expression of other transcripts associated with Tcm such as Tcf7 ( 35 ) , Id3, Eomes, Il7r ( 36 ), and Cd27 ( 12 ) which were also elevated.

There is a clear trend for decreasing values of σ e as the INT-WS 2 content is increased.

Cross-trial analysis of patients divided by tumor biopsy positivity for TILT-123 by IHC, demonstrated a clear trend in increased fold change from baseline in CD8 + , CD8 + PD-1 + , CD4 + and CD4 + Foxp3 + T cells in biopsies with confirmed TILT-123 transduction, as well as a decreased fold change in PD-L1 + cells, indicating an immunological response associated with TILT-123 transduction (Fig. 4 C).

Even in studies in which the difference did not reach statistical significance, there was a clear trend toward reduced FVC for smokers in most of them ( Table 3 ).

A clear trend is observed across all samples, with a pronounced increase in the absorption intensities corresponding to hydroxyl and carbonyl functional groups, accompanied by a noticeable decrease in the aliphatic C–H stretching bands as the UV exposure time increases.

After examining the survival rate graphs of LAB in sugar syrup and glucose + fructose syrup over 7 days, a clear trend favoring sugar syrup as a medium for supporting LAB viability is observed.

From Figure S8, it can be seen that the resistance of the PANI hollow nanotube sensor under varying humidity levels (0%, 25%, 50%, 75%) demonstrates a clear trend where the baseline resistance decreases with increasing humidity.

A clear trend towards the TL formation was observed for the CCF-reinforced composites.

For SM, both the 2025 and 2024 data show a clear trend in which severity increased with fillet weight across all production systems ( Fig. 1 ).

There was a clear trend towards higher inpatient mortality; however, this was likely limited by type II error.

Neutralizing IL-6 and TGFβ in co-cultures did not lead to a significant effect on memory formation, although especially in the case of IL-6, we found a clear trend towards a memory switch.

The accuracy values show a clear trend of improvement over epochs for both the training and validation sets.

There was a clear trend towards the inhibition of germination and seedling emergence with increasing rate of guano applied ( Figure 1 ).

Thus, we did not find a clear trend for the BIC between the implantation sites and bone types for either material.

With respect to prediction time steps, we observed a clear trend in both MDCK epithelia and HUVEC endothelia where the network accuracy improved with increasing time-steps, with data from either 20 min or 60 min forward predictions shown (red and blue lines in Fig 3D ; see attention maps in S11 Fig ).