“a clear trend”

Despite considerable variability in plasma exposure within each SLCO1B1 genotype, there was a clear trend in higher atrasentan plasma exposure with reduced hepatic uptake for the rarer variant SLCO1B1 genotypes.

5 indicate a clear trend between the Cu–L binding strengths and the stripping potentials.

Furthermore, a clear trend was observed for 25 Hz stimulation being more efficient with this respect than 300 Hz: we counted 3,260 ± 839 cells/mm 3 in the sham-treated group, 7,651 ± 930 cells/mm 3 (130% increase) upon 25 Hz stimulation, and 5,652 ± 854 cells/mm 3 (70% increase) upon 300 Hz stimulation.

Exploring students' preferences for learning methods revealed a clear trend.

Contrary to our proteomics analysis, we did not find the expression levels of sAnk1.5 statistically increased in LV from 1-year old R4344Q female mice compared to wild-type via immunoblotting, although we did observe a clear trend ( Hu et al., 2017 ).

The statistically significant difference is lost by 18 hpi; however, a clear trend persists with higher mean values for macrophages stimulated with LAM ( Fig 2A ).

Thus, whatever the parameter (force or energy) used to study adhesion, we observe a clear trend such as Adh G > Adh S2 > Adh S1 > Adh CML (Figs. 6 g, h), with little variations within the S2 layer, and therefore little dependence to the MFA.

The alcohol group was under-represented in this type of olives and did not present a clear trend regarding the effect on the thermal treatments that were applied.

However, in our study, none of the studied trajectories was associated with diabetes incidence, although, a clear trend towards engagement in physical activities was observed.

A clear trend in writing quality was observed through grade analysis, and average assessment grades improved by a full letter by the end of the course (from C+ to B+ average).

From these experiments, a clear trend emerged linking the size of the cyclic starting material 6 to the reaction outcome.

[3b] We see a clear trend towards less positive and even negative Δ G upon reducing the temperature in our calculations.

Applying the model to map individual dead trees for multi-year NAIP images over a test area, we showed that a clear trend can be identified in the count of dead trees per ha in spite of inconsistent performances across years.

There was a clear trend of particles being located near the outlet for ACH increasing from 3 to 5, while, from 5 to 7, the same conclusion could not be drawn.

As technology becomes part and parcel of our everyday life, there is a clear trend that this evolution is taking place in the realm of lifestyle and psychosocial interventions in knee OA.

Stratified RMSE values revealed a clear trend of increasing error at more extreme joint angles, with the highest RMSE (15.82°) occurring in sagittal elbow flexion beyond 135°.

Moreover, the smoothed terms partial effect plot for age do not show a clear trend for its interpretation, since it remains stable with alternative small variations across different ages (Fig. 5 ).

3B ) and we see a clear trend (but not significant) in p(high info) with horizon (p(high info)h1_average = 0.5146; p(high info)h6_average = 0.5486; t(81) = 1.75; p = 0.084; d = 0.24) (Fig. 3A ), consistent with participants using both types of exploration in this paradigm.

The exponent a, describing the ideality of the capacitive characteristics of the electrode, shows some variation as a function of iron content, but the changes are too inconsistent to show a clear trend.

[1] Although there was a clear trend in favour of resection rectopexy with a recurrence rate of 13% (suture rectopexy 26%, perineal rectosigmoidectomy 24%, Delorme's 31%) there was no significant differences declared in the randomised comparisons although substantial improvements in the quality of life were noted following all procedures.

In the free acidity ( Figure 10 A) and acetyl content data ( Figure 10 B), a clear trend can be observed: in the sample stored without any inhibitors, the deacetylation process was dramatically pushed until a lowering of the overall degree of substitution of the polymer (from cellulose diacetate to cellulose monoacetate [ 3 , 31 ]); a similar trend was also evident for RMPF stored in the presence of pure PVF and WP, for which the deacetylation was only slowed down.

There was a clear trend showing greatest mortality in PBS treated groups, compared with those treated with HRIG (lowest) and ScFv/RVG ( Figs. 6 , 7 ).

For the amplitudes of all these five oscillations (i.e., delta, theta, alpha, beta, and gamma), the independent sample t-test conducted separately on each electrode did not reveal any significant results after the false discovery rate (FDR) procedure, although there is a clear trend that the alpha amplitudes of the healthy controls were larger than those of patients over parieto-occipital electrodes.

Although the variation among different –BAr’ units with identical electron donor blocks was not entirely straightforward, a clear trend emerged: all ArBTZ-BT compounds exhibited lower magnitude of E red values compared to the corresponding ArBTZ-BP compounds with equivalent donor blocks.

This reflects a clear trend in equine wound research toward minimizing the number of animals involved, which aligns with ethical considerations and the principles of the 3Rs (Replacement, Reduction, and Refinement).