“a clear trend”

All together, we observed a clear trend toward greater protection with higher systemic TDF doses and higher TFV plasma concentrations.

A clear trend towards a larger percentage of shorter PNAG saccharides (1–5 GlcNAc units) was seen upon incubation of the enzymes with PNAG.

The US data sets provide information about the number of embryos transferred in fresh cycles from 2005 onwards (not FET cycles). In all three geographical areas, there is a clear trend towards the transfer of fewer embryos ( Fig. 3 ).

Our results, however, are in conflict with another study that reported a clear trend with S. japonicum eggs being predominantly located in the beginning and the surface of the stool [16] .

While the bands in this analysis overlap, there is a clear trend for the size of the active site residues, as manifested by the average Σ V vdw ranging from 907 Å 3 for MTPSs to 733 Å 3 for StTPSs, with an average decrease of 58 Å 3 between two consecutive TPS groups.

A representative British cohort study that measured the BMI at the ages of 3, 5, 7, and 11 years reported that the obesity group had a clear trend towards obesity from the age of 3 years [ 4 ].

Although the association between mucositis severity and cGvHD risk did not reach statistical significance in our patients, there was a clear trend, consistent with the finding of moderate-to-severe oral mucositis as an independent risk factor for cGvHD in a recent study with a larger sample size (230 patients). 20 Whether plaque S. sanguinis is citrullinated in these patients and can be found in the circulation or cGvHD target organs is worthy of further research.

This trial failed to reach statistical significance, however, a clear trend towards improved response rates and prolonged median progression-free survival (mPFS) of combined SSA treatment + VEGF inhibition compared to monotherapy SSA was observed.

Within only two months, the analytical values showed a clear trend towards normalization: growth hormone (GH) 0.305 ng/mL and insulin-like growth factor 1 (IGF-1) 302.6 ng/mL.

Spatial mapping of cells both positive for Ki67 and Pan-cytokeratin revealed a clear trend: the number of actively proliferating cancer cells was lowest within stromal regions and progressively increased with distance from the stroma-tumor interface, plateauing at approximately 300 μm ( Figure 5D , Supplementary Figure S5B ).

Although the shear bond strength data did not reveal a clear trend, the decrease in the Weibull modulus in the experimental group indicated that the adhesive was only slightly impacted by hydrolytic stress during TC.

In contrast, subsequent LC periods (attempts 20-85) showed a clear trend toward stabilization, with decreasing mistake frequency and reduced slope.

The disruption of membrane potential (ratio of red and green fluorescence) in response to TA+Cur treatment showed a clear trend in HCT116 cells (Con: 5.02 vs TA+Cur: 2.72); however this trend was not obvious in HT29 cells (Con: 17. 52 vs TA+Cur: 11.05).

The effect of RTA treatment on enhanced 3D island formation showed a clear trend on both Ag and Au NP thin films, where higher annealing temperatures led to well-defined and narrower absorbance spectra.

S3B and S5D) revealed a clear trend of decreasing modulation depths for TcA (1193-IAP) due to the disappearance of the short distances and increasing modulation depths for TcA (914-IAP/2365-IAP) due to the appearance of the short distances upon prolonged incubation at pH 11.2.

Indeed, BRP, Unc13A, Syn, and Dlg1 first increased almost linearly to arrive at a plateau at 30d to 40d (“early aging”) ( Fig 1B–1F ), while the ratios between activated, lipidated Atg8a (Atg8a-II) and inactive, unlipidated Atg8a (Atg8a-I) showed a clear trend of gradual reduction during early aging ( Fig 1B and 1H ), consistent with previous reports [ 10 , 35 , 46 ].

However, the CTN of the electronic states does not show a clear trend with the ion position and its value is always around 0.4.

For the composite sponges, there is a clear trend of increasing the phenolic contents with the rise in the marjoram oil for PVA-M0.1, PVA-M0.25, and PVA-M0.5 groups.

On the fMRI findings, BOLD results demonstrated a clear trend in hierarchical gradient patterns depending on abstraction levels in both age groups, while older adults exhibited overaction in frontal-associated regions.

The fitted peak positions, however, show a clear trend across the detector, which was not expected.

IPF and AFE patient samples showed a clear trend of OPN and IL18 upregulation ( Figure S2a,b ).

8 B) during the treatment period, MnO 2 @GA-Fe@CAI treatment showed a clear trend of inhibition with lower tumor weight and smaller volume than that of control, as well as the higher tumor inhibition rates 58.09 ± 5.77% (Fig. 8 C).

castaneum and found a clear trend showing that decreased doses of Cas9 RNPs result in the decreased gene editing efficiency ( Figures S3 B and S3C).

Although these correlations were moderate, the results did not reach statistical significance, indicating that higher health spending does not necessarily translate into greater alignment with international standards, nor does it imply a clear trend toward the inclusion of medicines not contemplated by the WHO.

A clear trend is observed, with ε1 increasing from 1.366 (pure PVA) to 1.609 (PVA-D3), indicating a higher density of localized electronic states in the doped films 70 , 136 .