Barely Significant
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“a clear trend”

19,461 sentences · 19,461 papers · 31,348 search hits before verification · confirmed specimen

Sighted at

p<0.09

Listed by Hankins (2013) · Otte et al. (2022)

In the literature

Results HGT evoked an increase in BP (+15.9%; P<0.001), HR (14.7; P<0.001), SaO 2 (+0.5; P<0.001) EtO 2 (+2.1; P<0.05) RR (+9.2%; P = 0.05) and MV (+15.5%; P<0.001), while sas-TQ was diminished (-8.12%; P<0.001), and a clear trend toward cc-TQ decline was observed (-11.0%; NS).
Other limitations of the available data on HAAs for read-across were the reliance on in vitro studies, the limited number of in vivo genetic toxicity or other mechanistic data available, the lack of a clear trend in the BMDLs as a measure of cancer potency, and a negative cancer bioassay for monochloroacetic acid (the only mono-HAA tested for carcinogenicity).