“a clear trend”

The age-stratified results reveal a clear trend favoring morning vaccination in adults aged 60 years and older, while this effect was less pronounced in subgroups younger than 60 years.

This concerned disease phenotypes, but there was also a clear trend towards higher disease activity in patients starting with anti-TNF agents ( Supplemental Table 1 ) suggesting that these aspects probably contributed to the choice of treatment.

While most functional groups included both up- and down-regulated genes, several immune categories showed a clear trend to lower expression in domesticated Bolaks salmon, especially immunoglobulins, complement system and innate antiviral responses (Table 2 ), and the number of down-regulated genes in these categories was higher than in wild Lærdal salmon.

In contrast to what is observed for the position of absorption and emission maxima, the fluorescence quantum yields follow a clear trend: upon increasing the electron accepting character of the aryl-C6, the fluorescence quantum yields of TAP4 in DCM drop.

At the local level, data on sinonasal 25(OH)D 3 are more limited but suggest a clear trend toward reduced levels in CRSwNP tissues [ 63 , 79 ].

In summary, there was a clear trend towards larger portion of daily caloric intake being consumed at night.

There is a clear trend observed where the stabilising agent (BF slag) influences the amount of Pb leached from the various ratio mixes; the concentration from 70/30 mixes were 5.1, 7.6 and 4.5 mg/kg compared to the 30/70 mix; 0.78, 0.21 and 0.05 respectively.

Overall, the results do not show a clear trend towards a single method or family of algorithms and most models performed comparably well.

Overall, keyword co-occurrence and thematic evolution analyses indicate that DN research has exhibited a clear trend toward increasing maturity and diversification over time.

Also, the rows and thickness of INL in the peripheral retina were decreased in the ~22- to 24-month-old/Veh rats compared with the ~5- to 6-month-old/Veh rats, and ~22- to 24- month-old/P021 rats showed a clear trend to rescue the number of rows ( Figures 1C,E,G ).

oryzae LMG23582(T), cultured under different concentrations of CH 3 OH (0.25%, 0.5%, 1% and 2%) revealed a clear trend in CK secretion, whereby the hormone production was intensified by the decreasing concentration of CH 3 OH in the growth media (Fig. 4 , Table S 2 ).

If, in Andijan and Fergana, there is a clear trend of land improvement from the period 2006–2010 onwards, it is clear that in Namangan and Syrdarya, the dynamics are more complicated, and after the periods of deterioration, improvement is only first noted after the period 2013–2017.

Nonetheless, the white-line peak positions (ROI1: 8350.0 eV; ROI2: 8350.3 eV; ROI3: 8350.7 eV) shows a clear trend shifting toward higher energy from the center region to the border region.

A clear trend of a decrease in AFP was observed during the regular postoperative follow-up.

The impact of temperature did not show a clear trend, since both low and high temperatures caused the highest carbohydrate increment, while medium temperatures were related with the lowest carbohydrate levels.

Moreover, there is a clear trend in having increased both TNF-α and sTNFR levels in non-survivor patients compared to survivors independently of eGFR.

Although tofacitinib trends appeared to be more predictable, both sets of measurements showed a clear trend—lower echography scores corresponded to lower disease state scores, which appeared to be significant.

The distribution of each point showed a clear trend of separation between groups and relatively good sample stability within groups.

Although our sample size was insufficient to achieve statistical significance, a clear trend was observed with 100% 90-day survival in low NET producers (neutrophil NET release < cohort median), compared with only 60% 90-day survival in high NET producers (neutrophil NET release > median of cohort) ( Figure 6A ).

However, an analysis of the GBD data does not reveal a clear trend in this regard.

The results indicate a clear trend of decreasing battery capacity with increased mileage.

When sorted by their MACS binding score, a clear trend emerged that weaker sites were disrupted at lower dose (Figure 5 C) and experienced greater changes (Figure 5 D).

The primary findings are summarized as follows: (1) At the macro-scale, a clear trend of enhanced mechanical performance with increased NMAS was established.

Although NOX4 was not statistically reduced, a clear trend of reduction was obtained.

These oncology cases also highlight a clear trend toward integrating multi‐omics data with sophisticated machine learning models to create predictive biomarkers that stratify patients and help identify tailored therapeutic options [ 73 , 74 ].