Quartile analyses in this age group show significant increases in β values across higher quartiles of ACAG, particularly notable in Q3 ( β = 11.55, 95% CI: 5.37, 17.73; p < 0.001) and Q4 (β = 12.75, 95% CI: 6.67, 18.83; p < 0.001), with a clear trend ( p < 0.001).
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There was a clear trend of increasing mortality in GIB patients with previous usage of anticoagulation therapy (OR 4.01 [95% CI 1.75–9.22], p = 0.001 ).
The HD-Hom and HR (Spe/Cho) groups showed even greater efficacy, with dry wounds and a clear trend toward healing (P<0.001).
Measuring the amplitudes of paired-pulse iGluSnFR signal transients thus revealed a clear trend towards lower PPR, hence higher P r values, with greater distances from the s. pyramidale (PPR mean ± SEM: 1.49 ± 0.01, n = 33; regression at p<0.001; Figure 3C ).
However, interaction analyses showed that the boroughs with unexpectedly low utilisation rates were also those not showing a clear trend between socioeconomic conditions and services utilisation (interaction p<0.001), suggesting that in these boroughs the occurrence of mental disorders in disadvantaged people was not captured by our analysis based on service utilisation.
Additionally, the 26–75% SBP-TTR group showed a clear trend of increased CVD risk compared with the 76–100% SBP-TTR group ( Table 2 ) (adjusted HR, 1.07; 95% CI: 1.03–1.10; p < 0.001).
Notably, the NR group had a significantly higher number of moderate-to-severe exacerbations in the prior 12 months (median 4.0) than other groups, with a clear trend across the remission categories ( p < 0.001).
Deceased individuals exhibited significantly higher mean WWI (11.56 ± 0.79) compared to survivors (11.24 ± 0.81), with a clear trend of increased mortality across higher WWI groups (p < 0.001).
There was a clear trend of improved glucose control with increasing gestational age for all the glucose indices in the combined group of women monitored by either rtCGM or iCGM ( p < 0.001, fixed effect, linear mixed model).
Baseline characteristics for nonimmune individuals (n = 1 549 989; 790 276 men [51.0%] and 759 713 women [49.0%]) are presented in Table 1 , for whom a clear trend can be seen toward lower mean (SD) age (51.6 [17.7] years vs 27.3 [15.5] years for 4 immune family members; P < .001), fewer medical diagnoses (myocardial infarction: 30 554 [2.0%] vs 3 [0.4%]; P < .001), lower mean (SD) income (€29 247/US $34 671 [€80 770/US $95 750] vs €9205/US $10 912 [€14 242/US $16 883]; P < .001), and a lower proportion of individuals who were born in Sweden (1 267 527 [81.8%] vs 534 [72.7%]; P < .001) as the number of immune family members increased.
All three components showed a clear trend of decrease in amplitude with increasing eccentricity [N1: F (6,54) = 27.07, p < 0.001; P1: F (6,54) = 21.73, p < 0.001; N2: F (6,54) = 20.98, p < 0.001].
In line with previous studies [ 12 , 13 ], all examined relationships between OIDP scores and subjective oral health measures were statistically significant and showed a clear trend in the expected direction; worst the subjective oral health rating, higher the OIDP scores ( p < 0.001).
The IPS showed a clear trend of increasing mortality risk across quartiles, with HR reaching 2.044 in Q4 ( P < 0.001).
When analysed alongside the FFR patient cohort, there was a clear trend in stress MBF and MPR values across all ischaemic categories (CTO with inducible defect, FFR ≤ 0.80, FFR 0.81–0.90, FFR > 0.90; P < 0.001 for both stress MBF and MPR) ( Figure 8 ).
In males, there was a clear trend toward greater BFP in the normal and overweight groups ( Figure 3 B, p < 0.001), but not in obese males ( Figure 3 B, p < 0.001).
If this is broken down between the cohorts, there is a clear trend towards CGS having fewer dual qualifications than FGS (CGS: 28.4%, n = 256; FGS: 42.9%, n = 256; CS: p < 0.001). 3.4.
In our study, there was a clear trend showing that with increased liver fibrosis there were similar rises in leptin levels, seen most significantly with elevated BMI (P<0.001).
In the KDM-BA population, survival analyses across different quartiles of TyG-related indices (TyG, TyG-BMI, and TyG-WHtR) revealed significant differences, with log-rank tests showing a clear trend of decreased survival in higher quartiles for both all-cause and CVD mortality ( P < .001 for all indices; Fig. 2 A–F).
A clear trend was evident for the category 30–60 min /week and above (cut-offs: 60 mins, 90 mins, 150 mins and 300 mins): patients with higher BMI spent less time on EPA ( P < 0.001, χ2 = 26.86–41.95; odds ratios in S2 Fig ).
There was a clear trend towards poorer neurological outcome for patients with delayed trauma center admission in univariate analysis ( P = 0.001).
Figure 1d shows a clear trend where invasive LVEDP increases as IVRT decreases, with the scatter of data points indicating a distinct downward pattern ( r = −0.524, P < 0.001).
34 After multivariable adjustment, a clear trend was found between categories of HbA 1c and CHD ( P <0.001) and HbA 1c and ischemic stroke ( P <0.001).
The distribution of resection extent differed significantly between groups (p < 0.001, χ 2 test), with a clear trend toward more radical resections in Group 2 (Cochran–Armitage trend test, p < 0.001).
As shown in Table 1 , there was a clear trend of CT features being more common in advanced stages (pT3 to pT4) and the tumor sizes increased with more advanced pT stages (F = 451.43, p < 0.001) ( Table 1 ).
There was a clear trend (Table 2 ) that height was greater with increasing degree of myopia, and the difference in height between all groups was highly statistically significant ( p < 0.001).