“a clear trend”

Compared to CON mice, a clear trend towards increased rectal temperature was observed in SUC mice ( p = 0.094), whilst SUC + PHE mice showed a significant higher rectal temperature.

Besides, there was a clear trend in LED for seasonal variation in MS ( p = 0.095; Table 2 ).

Although not significant, the OA group shows a clear trend towards higher BMD with respect to the Ctrl group, with p = 0.095 for FN-BMD, p = 0.053 for FN T-score and p = 0.1 for FN Z-score.

Contrary to extrafollicular area, a clear trend (p=0.0952) towards increased levels, both as frequency or normalized counts, of IFN-α2 hi cells in SLE compared to control follicles was found ( Figure 1F , Supplementary Figure S2B ), further supporting our transcriptomic findings.

The ALSFRS-R score was significantly lower ( p = 0.05, paired T-test) in the second clinic visit compared with the first visit, while a clear trend to increased values in MDSC percentage was observed ( p = 0.096, paired T-test).

Results At 3 months postoperatively, patients who had undergone surgery in 2020 showed a clear trend towards a higher frequency of extension deficits of ≥ 5° (18.8% vs. 4.3%, p = 0.097) or an inability to bend the knee ≥ 120° (23.3% vs. 10%, p = 0.197) compared to those who had received surgery in 2019.

At 3 months postsurgery, patients who had undergone surgery in 2020 showed a clear trend toward a higher frequency of extension deficits of ≥5° (18.8% vs 4.3%, respectively; P = .097) or an inability to bend the knee ≥120° (23.3% vs 10%, respectively; P = .197) compared with those who had undergone surgery in 2019.

As shown in Figure 6D , although the improvement in survival rate of mice treated with XBJ and Hydroxysafflor Yellow A did not reach statistical significance compared to the PBS group (possibly due to the limited sample size or insufficient observation duration), the XBJ group exhibited a clear trend toward prolonged survival (HR = 0.361, P = 0.097) and demonstrated the strongest protective effect, with a survival rate at the endpoint twice that of the PBS group.

For rats, there is a clear trend (p = 0.097) towards higher odds (OR = 6.25 and 95% CI {0.7; 58.82}) for bone metastasis development compared to mice.

Though there were no significant differences between the outcomes of subgroups with or without EBRT, the mOS values showed a clear trend in favor of EBRT (673 vs. 517 days, p = 0.0983).

A clear trend towards upregulation of the skin barrier proteins involucrin (IVL, 1.4-fold; p = 0.099; Fig. 2b ) and loricrin (LOR, 1.6-fold; p = 0.5218; Fig. 2c ), as well as the tight junction proteins occludin (OCLN, 1.4-fold, Fig. 2d ) and claudin-1 (CLDN-1, 1.2-fold, p = 0.036, Fig. 2e ) in FLG − compared to FLG + skin equivalents was observed, in line with previous reports from our group 13 .

Despite a clear trend towards diminished immunity against escape virus (64% vs 25%), the difference in infection outcome between challenge groups was marginally insignificant ( Fig 3E ; p = 0.0995).

Administration of AC2 resulted in a clear trend of reducing this value (by 16.4%, p < 0.1) compared to the Melphalan Group, while administration of AC1 resulted in a slight trend to decrease in the ratio.

Among the patients with ACLF 3, those treated with HIT also showed a clear trend for a higher 10-day ( p = 0.10) and a 30-day survival ( p = 0.086) compared with those treated with LIT ( Figure 3(c) ).

Under conditions where vesicular 5-HT accumulation was inhibited by Tbz, citalopram was similarly effective (EC 50 = 94.5 nM; 46.0–194.3 nM; 95% C.I.; log IC 50 not different from Ctrl, P = 0.58, F = 0.32, extra sum-of-squares F test), although a clear trend toward weaker maximal effect was observed (fit bottom = 26.7%; 9.7–43.6%; 95% C.I.; not different from Crtl, P = 0.10, F = 2.71, extra sum-of-squares F test).

A clear trend in the same direction was displayed by the left thalamus and right hippocampus ( p < 0.1, FWE corrected).

In the forced choice paradigm of the Y-maze, 4 out of 5 individuals showed a clear trend (p<0.1) towards deciding for the arm from which the sound of an artificial school of conspecifics was played back.

Although a clear trend was observed, the difference did not reach statistical significance (exact Fisher’s test: p = 0.10).

Additionally, a clear trend towards increased abundance of Lactobacillaceae was observed in the AC, which was attributed to an increase in an OTU related to Pediococcus acidilactici (p = 0.100 in lumen and p = 0.069 in mucus).

Although the difference was not statistically significant, there was a clear trend towards higher miRNA abundance in milk‐derived EVs ( p < 0.10).

In the LS, the difference seen in the number of fields on the forced side versus choice side was most stark when the animal was traveling away from reward (two-tailed two sample t-test t(218)=3.8 p<0.001), although there was a clear trend while the animal traveled toward reward (two-tailed two sample t-test t(254)=1.82 p<0.1) ( Figure 6G ).

On the other hand, patients with severe impairment of the renal function (eGFR < 30 ml/min/1.73m 2 ) showed a clear trend to more likely develop DRT (13.3% vs. 5.1%, p = 0.10), as compared to the opposite group, Fig. 3 a and b.

Interestingly, albeit not significant, we noticed a clear trend toward higher levels of 5hmC among early induced genes compared with later induced genes ( P = 0.1, SI Appendix , Fig.

There was also a clear trend towards reduction of secreted IL-13 in Cerk -/- animals (- 45%; p = 0.10 vs WT), which was observed neither with Sphk1 -/- nor with Sphk2 -/- animals.

Furthermore, there was a clear trend toward reduced MmiR‐199a ( P =0.1) expression levels and reduced expression in plasma ( P =0.5 for miR‐126 in plasma; P =0.1 for miR‐199a in plasma) in patients with CAD ( Figure 3 ).