Barely Significant
← all phrases

“a clear trend”

19,461 sentences · 19,461 papers · 31,348 search hits before verification · confirmed specimen

Sighted at

p<0.09

Listed by Hankins (2013) · Otte et al. (2022)

In the literature

aegyptiacus spatial transcriptomics data, enabled us to test where the orthologs of these zonation markers are expressed along the villus in an unbiased manner: We observed a clear trend where the orthologous bat genes of these zonation markers tend to be spatially expressed from proximal to distal regions of the section, matching the expected patterns from mouse ( Fig. 3b and d and supplementary figs.
The 5 min chromatographic run and subng/mL LOQs (Lyso-Gb1 0.380 ng/mL; Lyso-Gb3 0.756 ng/mL) met all ICH M10 criteria, with consistent accuracy/precision, stability, carry-over, dilution integrity, and reinjection performance. Clinically, the assay demonstrated a clear trend of separation between Fabry patients and healthy controls and showed excellent ROC performance (AUC = 1.000) with pragmatic cutoffs (5.80 ng/mL for Lyso-Gb1; 3.334 ng/mL for Lyso-Gb3), consistent with ranges reported in previous studies.
Surprisingly, considering the frequently reported loss of dopaminergic neurons in the SN of DLB patients, TH levels were not significantly reduced ( p = 0.17) but showed a clear trend towards a reduction in SN Surr. tissue of DLB patients (fold change CTRL/DLB: 2.9). 3.4. α-Synuclein Is Highly Abundant in NMGs of DLB Cases Since especially neuromelanin containing dopaminergic neurons are lost in the SN of DLB cases, it is assumed that neuromelanin or NMGs may be involved in the pathogenesis of DLB.