Barely Significant

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highly significantP < 0.00010.0× alphaqualifiedgold
The analysis of all SIV-infected animals revealed a highly significant inverse correlation between the viral RNA load in plasma and the CD4+ T-cells in blood ( P < 0.0001; r = -0.786), BAL ( P < 0.0001; r = -0.814), duodenum ( P = 0.008; r = -0.497) and colon ( P < 0.0001; r = -0.685) as well as for the proportion of CD4+CCR5+ T-cells in blood ( P = 0.0003; r = - 0.647), BAL ( P < 0.0001; r = - 0.817), duodenum ( P < 0.0001; r = - 0.742) and colon ( P = 0.0003; r = - 0.674).
highly significantp < 0.00010.0× alphaqualifiedgold
Quantitative analysis confirmed that TGF-β1 alone did not significantly alter VCAM-1 expression compared with control (Dunnett’s test: mean difference = −1.12, 95% CI −3.85 to 1.61, p = 0.42), whereas TNF-α treatment resulted in a highly significant increase in VCAM-1 fluorescence intensity (mean difference = −22.24, 95% CI −24.57 to −19.90, p < 0.0001).
highly significantP < .00010.0× alphaqualifiedgold
The time to first parasitemia is shown in a plot of the Kaplan Meier survival estimate in Fig 2 , indicating no significant difference between ARR and RRR groups by blood smear ( P = .46) and by PCR ( P = .41) in contrast to highly significant differences between ARR and RRR compared to infectivity controls ( P < .0001).
highly significantp < 0.00010.0× alphaqualifiedgold
Comparison of the MO versus MO breathing histogram ( Figure S3B ; Figure 4A , gray trace) with the odor discrimination tasks revealed a highly significant difference ( Figure 4 ; Kolmogorov-Smirnov [K-S] test, p < 0.0001 for all odor pairs), indicating that increased sniffing occurred only when mice were conditioned to discriminate odors.
highly significantp < 0.00010.0× alphaqualifiedgold
Trichomalus perfectus Parasitism Rate A highly significant but low negative correlation between T. perfectus parasitism rate and CSW infestation rate was observed ( Kendall’s Tau = 0.29, z = 4.31, p < 0.0001) ( Figure 5 ).