The global correlation across all time points remained highly significant (ρ = 0.65, p < 10 −4 ).
Excerpts
A highly significant correlation was found between the extension of CT intermingling and the frequency of translocations in lymphocytes ( p < 0.0001).
The highly significant positive phenotypic correlation between NCPP and SPP ( r = 0.90, p < 0.0001) and the negative correlation between those traits and TSW ( Table S4 ), may indicate compensation between yield components via morphological modifications [ 7 ].
The difference between controls and carriers is highly significant, P =0.0001 ( Table 1 ).
Insulin glargine resulted in a highly significant ( P < 0.0001) absolute reduction of mean daytime glucose level from baseline to end point: 9.9 ± 2.0 to 6.9 ± 1.5 mmol/l, which corresponds to −3.0 ± 2.1 mmol/l.
Strikingly, the activity in lymphoblasts showed a highly significant positive correlation with levels of DHRSX protein in this cell line (see Figure 1 J) (NADH: R 2 = 0.9667; p < 0.0001, NADPH: R 2 = 0.9910; p < 0.0001; Figure 3 E).
Moreover, there was a clear trend of increasing frailty risk with worsening sarcopenia severity, as indicated by the trend test ( p -value for trend: p < 0.0001).
Over-representation analysis (ORA) of these lists, performed using the Web-based GEne SeT Analysis Toolkit ( http://www.webgestalt.org ) [ 33 ], demonstrated a highly significant enrichment ( P < 0.0001) of the cell component gene ontology category “mitochondrion” for let-7c-5p and miR-155-5p downregulated targets, with a cluster of 26 and 8 genes, respectively (Tables 1 and 2 ).
Whereas the density of pancreatic stellate cells (PSCs) was not different in tissues isolated from control and FAEE-AP (72 h) mice ( n = 14 and n = 31, P > 0.54), the density of PMs increased significantly in FAAE-AP mice after 48 h ( P < 0.033) and was highly significant after 72 h ( P < 0.0001; Figure 2E, F ).
Since Mdm2 heterozygosity greatly delays tumor development in Arf -null mice that have both alleles of p53 , the difference in mean survival between p53+/+ and the p53+/− Arf -null Mdm2+/− mice was much larger than their Mdm2 wild-type counterparts and quite significant (p<0.0001, log-rank test; Fig. 2B , Table 1 ).
This two- to three-fold enrichment for HGT C was highly significant (binomial GLM, estimate = 1.18, SE = 0.07, P < 0.0001; Fig. 2 ; Supplementary Table 3 ) in both species at both timepoints.
In the gene-based analysis, 976 genes were found to have genome-wide association ( P ≤ 0.05) that could be defined as the nominally significant GWAS geneset (NSGG), 9 of which were suggestively associated with milk yield ( P < 10 −4 ).
The association between poor quality of sleep and the other outcome variables of mental health (depression, anxiety, and stress) was highly significant (p<0.0001).
Indeed, although a highly significant association was observed between MSI and CD8+ TIL expression (27 MSI CRCs were CD8+ and 34 MSS cases showed CD8 negativity, p = 0.0001), 15 out of 43 MSI tumors (35%) were CD8- (MSI/CD8-) and 12 out of 46 MSS tumors (26%) were CD8+.
Second Study Rooting success was associated with a highly significant interaction between rooting environment and hormone treatment (F 8,15 = 137.93; p < 0.0001), with the model explaining 99.3% of the observed variance (R 2 = 0.99).
In our study there was a highly significant difference in METS of sedentary and non-sedentary individuals ( P < 0.0001).
Both the length and diameter in clean, unpainted, Triton-filled tubes showed highly significant differences in terms of trapped insects: χ 2 = 43.7654, d.f. = 2, p < 0.0001 for height (set-up (5)); χ 2 = 109.2067, d.f. = 1, p < 0.0001 for diameter (set-up (2)).
The slope further increased to 199.8 in the 2010s and 379.3 in the 2020s, both showing highly significant growth rates ( p < 0.0001).
The decline with age was highly significant ( p < 0.0001 in lme).
Preliminary population genomics analysis The non-hierarchical AMOVA carried out on all four community samples for both datasets (BcgI and CspCI) detected a strong signal of genetic structuring across the study area, with highly significant (P< 0.0001) global F ST values of 0.20452 (BcgI) and 0.39327 (CspCI).
Correlations of the HR with ambient temperature and heat index were also negative and very highly significant ( P < 0.0001) in both sexes of the AGRs.
The relative risk of each stage by sex (women/men) was: Stage 1 , 0.72 (more in men); Stage 2 , 1.11; Stage 3 , 1.68; and Stage 4 , 9.29 (all three more in women); these sex-differences were highly significant (overall χ 2 [d f = 3] = 51.3, p < 0.0001).
We found a highly significant correlation between the extent of intermingling and translocation frequency ( p < 0.0001; Figure 2 B), such that higher levels of CT intermingling increase the chances of double-strand breaks (DSBs) being involved in rearrangements with other chromosomes.
The chi-square test of likelihood ratio was highly significant (χ2 = 782.15, p < 0.0001), indicating the model’s overall fitness.
Results In the exploratory phase, WFNS and age were shown to be highly significant predictors for the outcome (p < 0.0001 for both).