Interestingly, this difference, while being small, is highly significant (paired-sample t -test; N = 176 per group; p < 0.0001).
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VRS showed an increasing trend with the severity of care, p < 0.0001.
NHDF transfected with Smad2 siRNA exhibited a highly significant SMAD2 transcription decrease of 0.1 ± 0.01-fold ( p < 0.0001) compared to negative control siRNA-treated cells, which did not change due to activin A supplementation ( Figure 4 C).
Change in UCVA in logarithm of the minimal angle of resolution from preoperative value to every follow-up postoperatively was highly significant ( P < 0.0001) in both the groups [ Figure 2 ].
In addition, the difference between this specific distribution of TbMlp2 and a random distribution of centromeres in the nucleus was highly significant ( P < 10 −4 ).
From the variance analysis, it is shown that the p -value of the regression model is extremely significant ( p < 0.0001).
We found a highly significant interaction between the occurrence of native versus non-native amphipods and upstream distance ( Chi 2 value = 16.03, p value <0.0001; Fig. 1 ), reflecting that non-native species were mostly present at the outlet, while the native species were mostly present at the further upstream sites.
An overall effect of month of COVID admission on odds of ICU/HDU admission was highly significant (Wald test p < 0.0001).
Generally, temperature linear terms (X 3 ) were highly significant ( p < 0.0001) for most responses, except for FRAP and cyanidin-3-rutinoside responses.
The difference between VO 2 peak/kg values was highly significant among all pairwise comparisons ( p < 0.0001), excluding that between the 35–40 kg/m 2 and 40–45 kg/m 2 groups.
Among LAC patients with additional tissue section available for next-generation sequencing (NGS)-based analysis, 26/193 (13.5%) patients found positive for even low-rate EGFR-T790M mutated alleles at baseline were associated with a highly significant lower survival in comparison to those without (8.7 vs. 47.4 months, p < 0.0001).
According Table 2 , U-Net and DeepLabV3Plus achieved highly significant improvements ( p < 0.0001) with large effect sizes (Cohen’s d > 0.56), indicating substantial practical significance.
The difference is highly significant, chi-square test (asymptotic significance, two sided), P <0.0001 ( Table 4 ).
Another problem is that if a secondary variable shows a clinically important effect or is highly significant (for example, with P < 0.0001), as one of the secondary outcomes in Baggot et al.
Highly significant (P < 0.0001) variation was perceived among the study locations for the mean squares of disease incidence, severity, AUDPC, disease progress rate, TSW, and GY due to interactions of wheat cultivars and chemical seed treatments.
Overall, the unequal MHCY haplotype distribution in HAS and LAS is highly significant ( P < 0.0001).
A linear mixed-effects model with stimulation rate and pulse shape (rampUp and rampDown) as fixed factors and subject as random factor reported a highly significant effect of rate ( F (1,117) = 478.44, p < .0001) but not of shape ( F (1,117) = 0.05, p = .8154) or the interaction between rate and shape ( F (1,117) = 0.03, p = .8559) on the angle.
The detection accuracy of culture and PCR was assessed, and the coefficient of accuracy (k) was highly significant in the healthy (0.3103; P < 0.0001) and CP groups (0.1536; P < 0.0497).
The heterogeneity test between the three subgroups was highly significant (Kruskal–Wallis ANOVA test, P = 0.0001).
For the TbGK protein, there was no significant difference (p = 0.08) in RPP medians values between positive and negative sera ( Fig 3A and Table 3 ) compared to TcoCB1, TbWTL, and TcWTL, which showed highly significant differences (p<0.0001) between sera from infected and non-infected cattle groups ( Fig 3B ).
The data indicated highly significant (p<0.0001) difference in serum TGF- β 1 levels between men (mean value: 37.6 ± 0.12 ng/mL, N = 4888) and women (mean value: 35.1 ± 0.12 ng/ml, N = 4254).
The high-risk group had a highly significant decreased OS compared with the low-risk group (p < 0.0001, hazard ratio [HR] = 8.98, 95% CI: 5.06–15.94; Figure 4 C).
A Student t-test showed extremely significant differences between both surfaces ( p < 0.0001; see Figure 7 B), which allows us to conclude that Tz-BSA-coated plates combined with modified-TCO capture antibody greatly improve the ELISA sensitivity. 4.
There was a highly significant positive correlation between the rate of pigment production and of (−)-botryodiplodin production ( r = 0.96, p ≤ 0.0001, regression analysis) for the selected M. phaseolina isolates. 2.8.
The least square (LS) mean differences compared with placebo in SPID6 values for the 62.5, 125, 250-mg, and combined DFN-15 groups were −756.6, −1120.7, −1355.1, and −1076.9, respectively, which were statistically highly significant for all comparisons ( P < 0.0001, ANCOVA model).