Barely Significant

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highly significantp<0.00010.0× alphaqualifiedgold
Analyses by finer time periods suggested a constant decline in HBsAg seroprevalence nationwide between 1973–1984 and 2019–2021 ( figure 2A ), which was highly significant in a linear regression model (−0.20% per year, p<0.0001; APC=−3.77, 95% CI −4.15 to –3.38) ( figure 2B ).
highly significantp < 0.00010.0× alphaqualifiedgold
Moreover, when plastic particles used in toxicity testing were classified into 4 size classes, the effect of particle size on toxicity was highly significant (ANOVA, p < 0.0001), and the dependence of safe concentration (HC 5 ) on particle size was even more remarkable, with a slope b = 1.21 according to the equation: \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\log \;{\text{HC}}_{5} = 1.21\;\log \;{\text{S}}{-}2.10$$\end{document} log HC 5 = 1.21 log S - 2.10 where S is the mean particle size (μm) for each size class (r 2 = 0.92, n = 4).
highly significantP = 0.00010.0× alphaqualifiedgold
These differences were confirmed by ANOVA, in which F values for genotypic differences were highly significant ( P = 0.0001; Table 2 ) and coefficient of variation (CV) ranged from 16.5 to 28.6% for parental genotypes and from 40.0 to 83.7% for the RILs.
highly significantp = 0.00010.0× alphaqualifiedgold
The percentage reduction from baseline disability scores revealed substantially greater therapeutic efficacy in group B, with a mean reduction of 65.20% with a standard deviation of 14.67% compared to 46.26% with a standard deviation of 18.42% in group A, yielding highly significant differences (t = -4.187; p = 0.0001) and a large effect size (Cohen's d = 1.183).
highly significantp<0.00010.0× alphaqualifiedgold
In contrast to the open group of patients, the laparoscopic group experienced a significant increase in operative time with a highly significant statistical difference (p<0.0001), and the laparoscopic group experienced a significant decrease in post-operative pain score with an insignificant p-value.
nominally significantP < 1.00 × 10 − 40.0× alphagold
3 , 12 Among the 32 nominally significant gene-based associations ( P < 1.00 × 10 − 4 ), six (18.75%) were issued from a missense|LC (i.e., low-confidence LoF variants) burden set, 19 (59.38%) were issued from a pLoF burden set, and seven (21.88%) were issued from a synonymous burden set ( Supplementary Figure S1 ).