Barely Significant

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highly significantp < 0.00010.0× alphaqualifiedgold
Statistical differences were determinated through the one-way analysis of variance procedure followed by Dunnett’s multiple comparison test, comparing results between mock control and treated cells, Differences were statistically significant when p < 0.05 (*) (#) and highly significant when p < 0.0001 (**) (##) versus each respective mock control or untreated control group. 3.
highly significantp < 0.00010.0× alphaqualifiedgold
Conversely, infection with Foxo1 AdV significantly reduced hepatocyte Fgf21 expression, whereas shFoxo1 AdV infection significantly increased Fgf21 mRNA ( Figure 3G ); as both viruses dose-dependently affected Fgf21, the expected linear trend in Fgf21 expression was also highly significant (p < 0.0001).
highly significantP < 0.00010.0× alphaqualifiedgold
As shown in Figure 3 , rEg.P29 alone did not induce a significant increase in specific IgG at 20 weeks post-immunization, whereas the formulation with Quil A adjuvant elicited a highly significant increase in rEg.P29-specific IgG ( P < 0.0001), confirming that Quil A is essential for inducing a robust IgG-dominant humoral immune response in sheep.
highly significantp < 0.00010.0× alphaqualifiedgold
When we combined the changes in specific epitope-precursor abundances and the favored HIV selection within patients who shared the presenting HLA variant, we found a strong, highly significant host-specific bias toward residues that specifically decrease the yield of epitopes that the host could potentially target ( Table S4 , p < 0.0001 [HIV B] and p = 0.0005 [HIV C], sign test).
highly significantP < 0.00010.0× alphaqualifiedgold
Two-way ANOVA analysis showed a highly significant effect of stress on body weight gain [ F (1, 147) = 16.25, P < 0.0001], with a highly significant effect of day [ F (13, 147) = 6.617, P < 0.0001].However, Bonfferoni’s post hoc test showed no significant interaction between stress and day on body weight gain [ F (13, 147) = 0.468, P = 0.9393] ( Figure 3A ).
highly significantp < 0.00010.0× alphaqualifiedgold
A highly significant relationship was observed between the estimation of the first rotation and the overall results of the test ( p < 0.0001); participants who made an accurate estimation of the first rotation had lower average estimation error than those who made an inaccurate first estimation.