Barely Significant

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highly significantp < 0.00010.0× alphaqualifiedgold
Intergroup comparison showed a higher statistically significant difference using Kruskal–Wallis test when group I: n CaO when compared with group III: n MgO and group II: n ZnO with group III: n MgO were seen to be highly significant ( p < 0.0001*) ( Table 4 ).
highly significantp < 0.00010.0× alphaqualifiedgold
At the level of Ct values of our extraction methods, a highly significant, very strong positive correlation was demonstrated between the miRNeasy kit and the TRIzol and Universal kits (miRNeasy/Universal p < 0.0001, r = 0.980; TRIzol/miRNeasy p < 0.0001 r = 0.959), and a highly significant, very strong positive correlation was found between the TRIzol and Universal kits (TRIzol/Universal p = <0.0001, r = 0.965) ( Figure 3 ). 3.2.
highly significantP < 0.00010.0× alphaqualifiedgold
A significant increase in IgG immune response was observed in infected mice groups; specifically, the wild-type mice exhibited highly significant serum IgG response (>1,000-fold) to P. gingivalis ( P < 0.0001) and T. forsythia ( P < 0.0001), TLR2 -/- and TLR4 -/- mice showed significant IgG response to F. nucleatum ( P < 0.0001) and P. gingivalis ( P < 0.0001) (>90-fold), and TLR4 -/- mice had a robust level of IgG response to P. gingivalis ( P < 0.01) (>700-fold) ( Fig. 1D1–3 ).
highly significantp < 0.00010.0× alphaqualifiedgold
For a-wave amplitude, a two-way repeated-measures ANOVA with treatment and intensity as factors found that both were highly significant ( p < 0.0001 for both), and Bonferroni post hoc tests indicated significant pairwise differences in the three highest intensities tested (−1 to 1 log cd s/m 2 ).