Barely Significant

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highly significantp < 0.00010.0× alphaqualifiedgold
Results Quantity of DNA The test of the extraction protocols indicated that in the case of Qiagen Kit, on average, 8.15 ng (SE = 0.39, i.e., 815 ng/g of mandible) of DNA was obtained per sample, whereas the Promega protocol provided on average 19.20 ng (SE = 0.455, i.e., 1,920 ng/g of mandible) of DNA, and the difference was highly significant ( t test, t = 18.35, df = 17.65, p < 0.0001; Table 1 ).
highly significantP < 0.00010.0× alphaqualifiedgold
This analysis also revealed a highly significant enrichment for TATA-box utilization in the G1 population of each gene set ( P < 0.0001, Fisher's exact test), albeit larger in the tissue specific population, alongside an enrichment in Sp1 binding site utilization in the tissue independent gene sets ( Supplementary Figure S6A and B ).
highly significantp < 0.00010.0× alphaqualifiedgold
Results Applying a vote‐count strategy to search for the intersection of genes reported in multiple independent studies with a consistent fold‐change direction, followed by a Monte Carlo simulation, we identified 528 highly significant differentially expressed multi‐study genes ( p < 0.0001; 10,000 simulations).