Excerpts

The difference observed was statistically highly significant ( P = 0.0001).

At 12 weeks, the investigators noted a highly significant difference in mean percentage change in tumour size between the study and control groups (–20% vs . +19%, P <0.0001).

For total medication count, both the overall association and the nonlinear component were highly significant (both p < 0.0001) (Figure 1A ).

Pairwise comparisons of the frequency of CYP2C:TG, TA and CG haplotypes in any study cohort versus any 1 KG superpopulation disclosed highly significant differences (chi square p < 0.0001).

It is interesting to note that difference between ApEn values in the two groups was highly significant (p = 0.0001).

Although significant lack of fit was observed for some responses, the models were retained because they remained highly significant ( p < 0.0001) and exhibited satisfactory coefficients of determination and adjusted R 2 values.

These two tests reveal a highly significant difference (P< 0.0001) between the values of wing-shaped Procrustes in the females of the three species ( Table 3 ).

We found that performance on the digital cognitive battery and EC tau proved to be more predictive of diagnostic status than Aβ and performance on the digital cognitive battery was qualitatively better compared to tau, and this approached significance (digital cognitive battery vs cortical Aβ p < 0.0001, EC tau vs cortical Aβ p < 0.01, digital cognitive battery vs EC tau p = 0.07).

However, 139 were previously reported lamin interactors ( 3 , 17 ), a highly significant enrichment (two-tailed chi-square test, p < 0.0001; Supplemental Table S4 , Test 1).

For IZD, the model and linear mixture terms are highly significant (p-value < 0.0001), indicating that the concentrations of the essential oils have a significant impact on the IZD.

The association between poor quality of sleep and the other outcome variables of mental health (depression, anxiety, and stress) was highly significant (p<0.0001).

While this was highly significant by counts (Fisher’s Exact Test, p-value < 0.0001), using the alternative hypothesis that the true odds ratio is not equal to 1 with a 95% confidence interval gives only a slightly higher odds ratio of 1.302.

There was a highly significant correlation between 3‐epi‐25‐OH‐D 3 and 25‐OH‐D 3 concentrations ( r = 0.77, R 2 = 0.5911, slope = 0.0579, p < 0.0001).

For all interactions, the global null hypothesis test was highly significant ( P ‐value < .0001).

RESULTS: Aqua destillata and 10% glucose showed a highly significant higher (p ≤ 0.0001) specific impedance compared to the standard 0.9% saline (factor 360).

When comparing the SEDC group to all other phenotypes combined, the difference in the frequency of multiple ossification centers was highly significant (Fisher’s exact test, p < 0.0001).

The CC group showed no significant increase in cortisol during stress or drug cue exposure, while the CG group showed a highly significant increase in their cortisol response during stress ( t =4.25, df=109, P <0.0001, Cohen's d =1.46) and drug cue ( t =3.04, df=109, P =0.003, Cohen's d =1.04) relative to the neutral condition ( Figure 2 ).

There was a highly significant correlation between circulating in vivo HI and MN antibody titers and survival (p < 0001).

As noted above, PSWQ showed a small but statistically significant ( p = 0.0017) negative effect of Obs, and highly significant (all p < 0.0001) small-to-medium effects of the other facets.

Similarly, 58.6% (n = 17) of the controls had normal IGF levels in comparison with only 5.9% (n = 1) of the cases with normal IGF levels and was found to be highly significant ( P < 0.0001).

Statistical analysis (ANOVA) indicated a highly significant reduction in pain severity ( P < 0.0001) and related symptoms ( P < 0.0001) evaluated by Michigan Neuropathy Screening instrument, Total Symptom Score, and Neuropathic Pain Symptoms Inventory.

The highly significant difference between these two values (Z=49.36, p<0.0001) indicates that co-innervations are not random, and suggests the existence of cooperative or joint-causality mechanisms for the innervation and control of nearby chromatophores.

There were strong and highly significant associations (p < 0.0001) between Fe NO and sputum eosinophils, regardless of whether the data was expressed as percentage differential or cell count.

To determine statistical significance, we used a two-tier thresholding strategy: a genome-wide marginal significance threshold of p ≤ 1.0 × 10 −4 (uncorrected), and a Bonferroni-corrected significance threshold computed based on the number of SNPs analyzed within each linkage-defined region.

These observations were quantitatively corroborated by fluorescence intensity analysis, which revealed a more than 3-fold increase in the FAM channel signal in chemoresistant U251 MG/TMZ cells compared to that in U251 cells, with highly significant statistical differences ( P < 0.0001, Fig. 5E ).