Excerpts

ADC values and SUV showed a moderate but highly significant inverse correlation (r = -0.5144, p < 0.0001).

For △ spoIID and △spoIIP , differences observed in each stage are highly significant, with p < 0.0001.

The M group demonstrated the smallest reduction (p< 0.05), whereas differences in the other groups were highly significant (p< 0.0001) ( Figure 8B ).

IL-19 and beta-defensin expression were also strongly correlated with each other ( r = 0.81) and highly significant ( P < 0.0001), suggesting that both biomarkers are involved in the same pathway of psoriasis pathogenesis.

LRTI was also more frequent during the HBoV1 primary infection (5%) than during the next interval (0%) but was too rare for the difference to reach significance; however, when combined with URTI, the difference was highly significant (p<0.0001).

For the primary variable GIS the difference between placebo and verum after 28 days of treatment showed a highly significant (p < 0.0001) difference between placebo and verum (6.7 resp. 4.7 points).

CD73 − CD8 T cells from AML patients showed a trend of higher susceptibility to apoptosis manifested by significantly higher expression of CD95 expression ( P < 0.0001, Fig. 5 c).

The difference between the crop communities was highly significant when considering only those isolates derived from MRS media (Chi-sq = 65.9, P<0.0001).

Gender differences were also highly significant (p < 0.0001), with a prevalence of 48.5% among males compared to just 11.9% among females.

The measure of population differentiation, F ST , among the subgroups was 0.15 highly significant at P < 0.0001.

Among the 3D printed samples, the reduction was highly significant ( p < 0.0001), while the milled PMMA samples also showed a significant decrease in microbial adhesion ( p = 0.001) relative to the control.

Results We find a highly significant positive correlation between Pfirrmann grades and the gene expression of MMP1 (r=0.67, p=0.0001), MMP3 (r=0.61, p=0.0002), MMP10 (r=0.6701, p=0.0001), MMP13 (r=0.48, p=0.004), ADAMTS1 (r=0.67, p=0.0001), and ADAMTS5 (r=0.53, p=0.0017).

The model exhibited a highly significant F -value of 42.89 ( p < 0.0001), indicating that the observed variation in the response could not be attributed to random noise.

The difference between the unconditioned and PBM conditioned light damage groups was highly significant ( p<0.0001 ), as were the differences between the saffron-conditioned and unconditioned groups ( p<0.0001 ), and between the combined-conditioned and unconditioned groups ( p<0.0004 ).

Statistical analysis revealed a highly significant effect of the nerve type ( p < 0.0001), accounting for approximately 85% of the total variance.

Statistical significance was defined as p < 0.05 for significant differences and p < 0.01 for highly significant differences, with **** indicating p < 0.0001, *** p < 0.001, ** p < 0.01, and * p < 0.05. 3.

Typhi and “No Growth” groups were highly significant ( P < 0.0001), the latter group contained a large number of outliers that may correspond to blood culture false-negatives.

Given that these two gene expression measurements were conducted independently and on different RNA extraction batches, the observed agreement in fold change for 110/161 genes is highly significant (one-tailed Fisher’s Exact Test, p < 0.0001; Additional file 2 : Table S4).

The incidence was 7.9% (79 of 994) in statin group and 14% (140 of 992) in control group, demonstrating that high-dose statin therapy preloading before PCI had a favorable trend toward the following outcome and reduced the incidence of MACE (OR=0.53, 95% CI: 0.39 to 0.71, p<0.0001) ( Figure 5 ).

Storage time interactions had significant ( p < 0.01) and highly significant ( p < 0.0001) effects on the syneresis and water‐holding capacity values of the samples, respectively.

The changes in ExitLOS and HistLOS are highly significant (P < 0.0001) but in opposite directions.

The activity of each tested caspase increased linearly after incubation with palmitic acid, becoming highly significant starting from 8 h (p<0.0001) ( Figure 4A ).

The pretest vs post test values of the WOMAC scale for patients with knee OA within both groups were found to be extremely significant ( P < 0.0001).

This is quantified in the Table 1 where cannabis use in 2015 is shown to be significant ( P = .0063), and for cannabis use in 2018 both cannabis use itself, and cannabis use in interaction with time are shown to be highly significant (both P < .0001).

Plate counting assays revealed a significant reduction in bacterial viability in the 3D-NEBS group relative to all control groups (Control, GelMA and 3D-BS), with highly significant differences (**** P < 0.0001; Figure 5B and C ).