The results of the multivariate T 2 test shows a highly significant effect of RAC ( T 2 = 415, p < 0.0001), with a large increase in LDS (73% in average).
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2a , b ) and a highly significant decrease in IFN-γ + secreting Th cells ( p = 0.0001, Fig. 2c , d ), as compared to both control groups.
Interestingly, these initiation peaks were enriched (68%) in the genomic segments 5 kb upstream or downstream of the TSS, and this correlation was highly significant compared with random (p < 0.0001; Figure 4 , A and B).
The observed uneven geographic distribution of both A.1 and A.4 is statistically highly significant ( P < .0001, two-tailed Fisher’s exact test).This distribution of subtypes in single larvae is also well represented in the pooled samples LdMNPV-SB, -SU, and -SZ, where for the northern samples -SB and -SZ also A.1, B.1, and C.1 was predicted, whereas -SU was explained by a combination of B.2 and B.3.
Relationship between patterns of CCSVI and clinical course We also found a highly significant difference in the distribution of the clinical courses among the CCSVI patterns (p<0.0001, χ 2 test) ( table 4 ).
ANOVA confirmed the model's predictive accuracy ( Table 4 ): the regression was highly significant ( F = 17.2075, p < 0.0001, R 2 = 0.9907), and the adjusted R 2 (0.9786) and predicted R 2 (0.9274) agreed to within an acceptable margin (Δ R 2 < 0.2).
The Kaiser-Meyer-Olkin measure of sampling adequacy was .94, and the Bartlett’s test of sphericity was highly significant (chi-squared = 1399.29, df = 44, p < .0001).
Highly significant difference were also found between the scores of four education groups (p = 0.0001).
Differences between diameters and heights in the two groups are extremely significant (Student's t test; P < 0.0001 in both cases).
ParaHIT Total showed lowest sensitivity (OR 0.08, 95% CI 0.04 - 0.19) and highly significant statistically (P < 0.0001).
[ 4 b] gives: 8 which is a highly significant relationship ( p < 0,0001, see Fig. 4 ).
Coexpression of hAG-2 and hAG-3 in the breast tumour tissues was highly significant ( P <0.0001).
A linear regressing analysis was also performed on the data from the HT assay and AHT device ( Figure 3 B), which demonstrated a highly significant correlation coefficient close to one ( R 2 = 0.998, p < 0.0001).
A two-way ANOVA revealed a very highly significant difference in cytotoxicity between GSE and GSE-TiO2NPs ( P < 0.0001 ) across all concentrations (Fig. 10 ).
We tested the associations of the vaccine-induced responses with measured serum neutralizing titers (NT 50 ) and observed strong and highly significant correlations, the highest with P3-II (Spearman CC = 0.88, p < 0.0001, Figure 5 A).
Combining the pollinator catches for each sampling week showed a highly significant difference (F 6, 890 = 29.4, p < 0.0001) among the sampling weeks, with a steady increase from the first sampling week (25.25 ± 3.79) through the fifth week, with the highest peak occurring on week six (154.75 ± 19.90) ( Figure 3 ).
Results Both models revealed a highly significant disparity in work stress among the different groups ( P < 0.0001) ( Table 2 ).
Highly significant (p < 0.0001) and close (Spearman r = -0.91) correlation between binding affinities determined by SPR and the mol% binding determined in the pull-down assays was observed for the interactions of both wild-type (closed symbols) and ΔH C loop-mutant (open symbols) H C B (triangles), H C DC (squares), and H C G (circles).
Microcystis cell density was estimated by converting the OD at 750 nm into cell density (cells ml −1 ) based on the highly significant positive correlation between these two parameters (R 2 = 0.96, N = 44; P<10 −4 , data not shown).
The rise in seroprevalence between 2023 and 2025 was highly significant across sexes, regions, and provinces (p < 0·0001; Table 2 ).
The difference of FP2 labelling between CCC and HCC was therefore highly significant (P < 0.0001) (p = 4.50794 e 10 ).
Survival benefit and safety profile Kaplan–Meier survival analysis revealed a highly significant intergroup difference (log-rank test, P < 0.0001).
Regarding the HO-1d mRNA expression, a highly significant increase ( p < 0.0001) was observed in the liver samples of the old group compared to both the young and the treated animals ( Figure 1 c), while at the pulmonary level, this rise was not significant.
To isolate the association of ideation with attempts, we found the residuals of the linear regression from panel B and plotted them against attempts, which still showed a positive trend (p<.0001).
Compared to sham-NT piglets, HI-NT piglets had a highly significant decrease ( p < 0.0001) in the ratio of normal-to-total neurons ( Supplementary Material Figure S10B ) and a highly significant increase ( p < 0.0001) in the ratio of ischemic-necrotic-to-total neurons ( Supplementary Material Figure S10A ).