Both time and anticoagulant had a highly significant effect on the plasma levels of PF4 and TSP-1 (p<0.0001 for time and anticoagulants).
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Repeated measures ANOVA showed highly significant effects of age (p<0.0001), the interaction of age with Lepr genotype (p<0.0001), the interaction of age with BN congenic genotype (p = 0.0055), and lesser significance for Lepr genotype and BN congenic genotype interaction (p = 0.0330).
Variation of hominin body size by time Linear regressions of body size by chronometric age ( figure 1 ) find a strong positive and highly significant correlation with body mass ( F = 226.551; p < 0.0001; R 2 = 0.475; d.f. = 250) and stature ( F = 125.337; p < 0.0001; R 2 = 0.384; d.f. = 201).
Comparison of the Puncture Depth Between the Ipsilateral Ventricle and the Contralateral Ventricle The difference in the puncture depth between the ipsilateral ventricle and the contralateral ventricle was extremely significant ( P < .0001); the depth of puncture to the ipsilateral ventricle in 373 patients was less than 60 mm, and the depth of puncture to the contralateral ventricle in 37 patients ranged from 52 to 65 mm (Figure 4 D).
More importantly, we found a highly significant effect of the workload manipulation on HR [ F (1, 18) = 36.1431, p < 0.0001, η 2 p = 0.667], with a higher HR for the more challenging 2-back task (mean = 80.4 ± 9.89) compared with the relatively easy 0-back task (mean = 77.27 ± 10.19).
The model was highly significant ( P < 0.0001) with a non-significant lack of fit ( P = 0.09 > 0.05), confirming the model’s reliability and predictive validity for process optimization.
In histological subsets, 90 % of the squamous cell carcinomas expressed high levels of HMGA2, while 47 % of the adenocarcinomas showed high expression of the protein; this difference was highly significant ( p < 0.0001).
Nonparametric ANOVA was extremely significant ( P < 0.0001).
There has also been a significant trend toward prolonged survival time in patients treated on the control arms initiated over the entire period of the analysis (1972 to 1993, P=0.0001).
There were highly significant differences between the classes, with initially Robust participants surviving longest and the initially Frail shortest (log rank test = 190.2, 3 df, p < .0001).
These were highly significant differences comparing the four versus two times daily ( P <0.0001, P <0.0001 and P <0.0013) and four versus one time daily ( P <0.0001 in each cohort) schedules.
Highly significant correlations ( P < 0.0001) were observed between all the four neutralization assays employed in this study ( Fig. 4E–J ).
Repeated measures ANOVA followed with Fisher’s PLSD posthoc test showed a highly significant difference between negative and positive controls over time (p<0.0001), but no significant difference between the two negative control pools or the two positive control pools for Libraries I and II, despite the large number of samples (p = 0.1208 and p = 0.2659, respectively).
The models highlighted below were all highly significant ( p < 0.0001).
The difference in the proportion of inhibitory and excitatory PPD cells between the L4 and L2 segments was highly significant (Fisher's exact probability test, p < 0.0001).
Analysis of variance showed highly significant effects of genotype on both traits (PY: p < 0.0001; BLB: p < 0.0001), indicating considerable genetic variation among the lines.
Not surprisingly, combining cases in both of these early neuter periods also revealed a highly significant increase above that of intact males ( P < 0.0001, hazard ratio = 3.79 [1.95, 7.37]).
Compared with placebo or control, L-carnitine was found to be associated with a highly significant 65% reduction in ventricular arrhythmias (RR = 0.35; 95%CI: 0.21-0.58, P < 0.0001, I 2 = 0%)[ 71 ].
Loss of p53 function produced a highly significant reduction in time to reach humane endpoints - median survival (Fig. 5D ; median 34.5 days vs 90 days; p < 0.0001).
The effect of both Dex treatment and tissue type on dispersal of GBM-2 and GBM-3 were found to be extremely significant (p<0.0001), as was the interaction between those two variables (p<0.0020 and <0.0001 for GBM-2 and GBM-3, respectively, Table 1 ).
However, the decline in body temperature observed during the course of infection was more evident from day 5 pi, and was highly significant (F (7, 48) = 84.318, p < 0.0001) ( Figure 2 b).
CT exposure resulted in a highly significant ( p < 0.0001) increase of FPC in all four individuals with an average DSB foci number of 0.66 ± 0.08 for PCCT and 0.56 ± 0.067 for conventional CT (Fig. 2 ), in addition to a significant difference among both CT techniques ( p < 0.004).
For the risk level model (Table 3 ), the Spearman rank correlation coefficient between the originally measured PROCAM scores and the corresponding predicted risk level values was 0.74, which was highly significant (p < 0.0001).
The model for VS was highly significant (F = 65.10, p < 0.0001) with a coefficient of determination (R2) of 0.991, an adjusted R2 of 0.976, and a predicted R2 of 0.864.
Of these SNP, rs29025980 showed a highly significant ( P < 0.0001) departure from Hardy Weinberg Equilibrium (HWE) in almost all groups tested (5 out of 8 breed types).