With respect to X 0 , all variables were highly significant (P < 0.0001) and were therefore included in the final model (detailed in Supplementary information: model outputs).
Excerpts
Distal femora from young adult ptx3 −/− females (10–12 weeks old) on B6 background showed highly significant decrease in trabecular bone volume ( p < 0.0001), which was paralleled by decreased trabecular number and trabecular thickness, as well as increased trabecular separation compared to ptx3 +/+ mice (Figure 1 ).
Statistical analysis of variance (ANOVA) revealed that, while there was a highly significant effect for sex ( F (1, 131) = 873.4, P < 0.0001), there was none for Wolbachia ( F (1, 131) = 0.03728, P = 0.8472).
Statistical analysis revealed a highly significant ( p < 0.0001) concentration-dependent reduction of ferric to ferrous iron by the sourdough extract, indicating a notable ability to donate electrons and act as a reducing agent.
Statistical analysis revealed a highly significant association between diffuse p53 protein expression and p53 missense mutation in these tumours (Table 6; Chi-squared, P < 0.0001).
Overlay images of the red and green channels from immunofluorescence co-staining demonstrated distinct patterns of expression, where analysis of MOC K1 and K2 indicated a highly significant negative correlation (Spearman's correlation, −0.8767, p < 0.0001) between GPX4 and Vimentin protein levels ( Fig. 5 K).
The mesh count raw data (Figure 2 C) show that 40 nM Ov -GRN-1 increased the mesh count from the medium only control of 9.7–15.7 meshes—a highly significant ( P < 0.0001) relative increase over the blank control of 62% (Figure 3 A).
Table 3 illustrates that the response surface model had an excellent fit and was highly significant, as 96.59 % of the predicted findings were within the experimental range (R 2 = 0.9659, p < 0.0001, and F = 28.31).
Statistical analysis revealed a highly significant difference between the control group and the dropped group ( p < 0.0001), indicating the substantial contamination risk when grafts were exposed to the operating room floor.
The ANOVAs for both size and shape reveal that the main effect of ‘tooth germ’ is highly significant ( P < 0.0001) compared to digitizing error, meaning that digitizing error in placing landmarks on tooth germs is highly negligible ( S1 Table ).
Two-way ANOVA showed a highly significant treatment effect ( F (1,20) = 47, p < 0.0001), time effect ( F (4,20) = 91, p < 0.0001), and interaction effect ( F (4,20) = 11, p < 0.0001), indicating a time-dependent pharmacological inhibition of DAT functions.
The difference between the groups was highly significant ( p < 0.0001).
On the other hand, the differences were highly significant (P<0.0001) in 2 of the 3 markers and the three different proliferation biomarkers all point into the same direction.
There were highly significant associa- tions between MIB 1 score and histological type (X2 = 22.62, P < 0.0001) as well as histological grade (X2 = 22.21, P < 0.0001).
Differences within groups were marginally significant or non‐significant, while the difference among groups was highly significant ( P < 0.0001).
In the early group linsitinib had a highly significant effect on GD development (p ≤ 0.0001) ( Figure 9E ).
Protection was dose dependent, and there was a highly significant correlation between circulating in vivo HI and MN antibody titers and mice survival (nonparametric Spearman correlation r = 0.9, P < .0001) ( Hohenadl et al., 2014 ) A RCT of patients hospitalized with severe A(H1N1)pdm09 virus infection in 5 hospitals in Hong Kong compared treatment with immune IVIG prepared from plasma of persons who had recovered from the disease against treatment with normal IVIG manufactured before 2009 ( Hung et al., 2013 ).
The variance components estimates for genotype and genotype by environment interaction were highly significant ( P < 0.0001) for all locations and across environments ( Table 2 ).
For all interactions, the global null hypothesis test was highly significant (p-value < .0001).
The prognostic value of the 'natural' S-phase fraction was highly significant (Table 1 and Figure iB), which was also true if the cut-off was set at 2.0%, 2.5%, 3.5% or 4.0% (P < 0.0001 in all cases).
For each metal the GLM model was highly significant ( p < 0.0001) (Table 1 ).
Correlations of HOMA-IR HOMA-IR was highly significantly and positively correlated with hepatic triglyceride content (r:0.76;p<0.0001), and other less highly significant positive correlations were found with waist circumference (r:0.52;p<0.001), BMI (r:0.48;p<0.01), age (r:0.49;p<0.01) and serum ALT (r:0.3;p<0.03), while inverse correlation with serum adiponectin (r:0.47;p<0,01) and HDL-C (r:0.46;p<0.02) were observed.
However, a highly significant difference was found among participants with different education levels (p < 0.0001).
The genetic differentiation among the populations was high (F ST : 0.28) and found to be highly significant ( p < 0.0001).
Interestingly, we observed a highly significant reduction in P2X3-labeled nerve fibers within the total fungiform papilla area ( Fig. 4 A and C ; 29.0% reduction; P < 0.0001).