The overall F-test from ANODIS was highly significant (P < 0.0001, Table 2 ).
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When the repeat number added to the expanded allele in each organ from multiple animals was averaged, the effect of the loss of one or both Mlh3 alleles was found to be highly significant for all organs ( Fig 1B ; p < 0.0001).
The log-rank test for the overall difference among the four survival curves was highly significant ( P < 0.0001), providing strong evidence against the null hypothesis of no difference in survival distributions between the CTI groups.
Key Findings • The mean percent decrease from baseline in ulcer area over the treatment period was highly significant for both the collagenase ( p < 0.0001) and for the silver ( p < 0.0001) treatment groups. • Ulcers treated with clostridial collagenase had a 55% greater mean reduction in area from baseline when compared with the silver control group at the end of treatment ( p = 0.071). • Silver treatment provide
RML-inoculated transgenic mice reached terminal disease after 400 ± 56 dpi (n = 10), whereas WTPrP C mice became terminally sick at 155 ± 1.6 dpi (n = 8), thus also showing a highly significant delay for PrP C GPIThy-1-expressing mice (Log Rank (Mantel-Cox)**** p <0.0001; S6A Fig ).
Similarly, a highly significant regional difference was detected for A. phagocytophilum ( P = 0.0001), with the highest seroprevalence observed in Western (23%, CI: 14–30), Southern (22%, Cl: 14–31), and Central Norway (14%, CI: 3–36), compared to a markedly lower seroprevalence in Eastern Norway (2%, CI: 1–6) and no positive samples detected in Northern Norway (0%, CI: 0–13).
The model was highly significant ( P < 0.0001) with a non-significant lack of fit ( P = 0.09 > 0.05), confirming the model’s reliability and predictive validity for process optimization.
The analysis of extracts spiked with known concentrations of the compound ( Figure 3 c) showed a highly significant correlation between P5C concentration in samples and its estimation ( p < 0.0001 in a Pearson two-tailed test) and allowed us to evaluate the recovery (about 85%) and to estimate the detection limit of the method (about 20–30 nmol g −1 FW under the experimental condition used).
extremely significantqualified
* p < 0.05, significant; ** p < 0.01, very significant; *** p < 0.001, highly significant; **** p < 0.0001, extremely significant; n.s., not significant.
Relationship of thiamine, mortality and body size with fatty acids In the M74 year (1998), YSFM among the offspring of all female salmon had a highly significant negative correlation with the concentrations of THIAM ( r = − 0.811, P < 0.0001) and TotTHIAM ( r = − 0.805, P < 0.0001) in unfertilized eggs and also a correlation with the TMP ( r = − 0.539, P = 0.012), but not with the TPP concentration ( r = − 0.283, P = 0.214).
Body mass index reductions after LSG were highly significant compared to baseline values at all time points over 10 years ( p = 0.0001) and remained significantly lower for up to 7 years post-KT.
The regression model was highly significant ( F = 41.35, p < 0.0001), whereas the lack-of-fit was statistically insignificant, demonstrating that the model adequately described the experimental results.
Oregano Oil Significantly Reduced Bacterial Burden in Burn Wounds Infected With USA300 As shown in Figure 5A , an average reduction in bacterial luminescence of 2.9 log 10 was attained when the infected wounds were treated with oregano oil at 5 mg/ml for 40 min, which was highly significant compared to only 0.4 log 10 decline of the bioluminescence in the absence of oregano oil during the same period ( P < 0.0001; Figure 5A ).
In addition, the quadratic term X 3 2 (LOR2) was highly significant ( p < 0.0001), along with a large negative coefficient (−272.987), confirming the strong nonlinear suppressive effect of higher LOR concentrations on the nanoparticle size.
Results KaplanMeier analysis showed a highly significant difference in OS between the CMR and N-CMR groups (log-rank test p < 0.0001).
The correlation we observed was highly significant (for Pearson’s product-moment correlation, P < 0.0001; not reported in the original publication).
For example, Fig 5 shows one example of a highly significant relationship between the date and phi (β = 1.779, p<0.0001).
Also, the random effects were not centered on 0, with highly significant deviations ( p < 0.0001) for the apparent central volume of distribution (V2/F), the apparent peripheral volume of distribution (V3/F), and T lag ; and the largest deviation corresponding to a 43% higher V2/F.
The difference between survival curves was highly significant for PRS2 (p < 0.0001).
Statistical significance was determined using ordinary one‐way ANOVA, with highly significant differences (**** p < 0.0001, *** p < 0.001, ** p < 0.01) for comparisons between consecutive groups, while “NS” indicates nonsignificant statistical difference between the data groups.
The ROC curve plotted to evaluate the value of SC percentage for prediction of positive ZAP-70 expression revealed a highly significant area under the curve of 0.936 ( P =0.0001) with a cutoff value of 8.5% and sensitivity 0.966 ( Fig. 2 ).
The differences in Q ′ values between the control and CVD cohorts are highly significant, with two-tailed p -values < 1 × 10 −4 (Fig. 3 and Supplementary Table S3 ).
This difference was highly significant ( p < 0.0001), indicating a significant enhancement in urinary function and overall quality of life in patients in the treatment group.
A GLM with a negative binomial distribution with a log link function showed a highly significant positive effect of nest type on the number of trips per female [slope = 2.902, t = 7.078, P < 0.0001, dp = 1.119; dp is the dispersion parameter of the model, and when this is 1, the dispersion of the data from the model is within the predicted variance from the model (meaning the model fitted well to the observed data)].
Comparison of normal mucosa, tumor-adjacent mucosa, and tumors disclosed a strong and highly significant (p < 0.0001) up-regulation of EpEX in tumors with median IHC scores of 220 versus 60 and 50 in tumor-adjacent and healthy mucosa, respectively (Fig. 1d ).