Excerpts

Friedman's analysis of variance revealed that there was a highly significant variation at all frequencies (p = 0.0001).

In addition, viral titration of the supernatants displayed a highly significant ( p < 0.0001) reduction of extracellular viral infectivity ( Figure 3 B–G).

A concomitant positivity of NPT and nasal IgE test to Alternaria was observed in about 70% of patients, while positivity of SPT and NPT was observed in 27% of patients, this difference being highly significant (p < 0.0001).

All the differences between the different network types were highly significant ( p < 0.0001).

These two antigen assays showed a highly significant correlation with a Pearson’s r of 0.96 ( p < 0.0001) ( Supplementary Figure S3 ).

The perindopril trials demonstrated a highly significant event reduction (OR 0.78; 95% CI: 0.72–0.85; p < 0.0001 (Fig. 4) .

0119), thereafter extremely significant difference began to occur (Kruskal-Wallis test p < 0. 0001).

Both cell lines exhibited a marked decline in cell numbers for each siRNA relative to the negative control (Figure 5a and 5b ), along with a highly significant increase (3.9 fold; P < 0.0001) in the late apoptotic cell fraction assessed by FACs analysis of an annexin V staining assay (Figure 6a and 6b ).

The difference between the unconditioned and PBM conditioned light damage groups was highly significant ( p<0.0001 ), as were the differences between the saffron-conditioned and unconditioned groups ( p<0.0001 ), and between the combined-conditioned and unconditioned groups ( p<0.0004 ).

Similarly, the correlation of the infection neutralization capacity of Omicron BA.1 and NAb was highly significant ( p < 0.0001) and moderately (rho = 0.44) positive.

The p -values of the linear regression analysis were highly significant in all three studies (p < 0.0001).

As this factor showed a highly significant effect on the HD AAO (P<0.0001), we split the HD patients of the EHDN REGISTRY cohort as well as the 1 st European HD cohort by ancestry and analysed the impact of the ATG7 V471A polymorphism in these single groups.

Although risk group classification was highly significant on univariate analysis (p=0.0001; worsened outcome with increased risk group), this finding disappeared on multivariable analysis.

Following a 24 h exposure period, both cell models showed a highly significant response to the compound ( p < 0.0001) at 2.0–5.0 μM, with non-significant responses at 1 μM.

Both were highly significant, priming SOA: F (1, 19) = 31.1, p < .0001, MSE = 129.9, task: F (2, 19) = 8.3, p < .001, MSE = 72.13.

Both these associations were highly significant (p-value<0.0001).

41 As shown by the results, treatment by free DOX (G 4 ) caused an extremely significant cardiotoxicity as compared to normal control (G 1 ) ( P < 0.0001).

These revealed that the difference in mean activity between winners and losers was highly significant in the case of strong dominance pairs (W = 0.39; L = 0.20; Mann–Whitney U = 1, df 23, P < 0.0001).

There was a significant trend towards outpatient treatment over the study period ( p < 0.0001).

This showed a highly significant increase between the second (1 week after the second dose) and third dose (2 weeks after the third dose) for Omicron (p < 0.0001), less for Beta (p < 0.005) and not significantly different for original WT and Delta VOCs ( Figure S2 ).

Discrimination followed the order IL‐2 > IL‐13 > IFN‐γ with, however, only subtle differences in the respective highly significant AUC (0.9310, 0.8994, 0.8316) values (all p < .0001; Figure S7 A), which was similar to the results obtained with gradient‐purified PBMC with regard to IL‐13 and IFN‐γ while IL‐2 levels were clearly lower and less discriminatory after 6 days (Figure S4 A).

However, a highly significant difference was observed among the groups for pain scoring, with a p-value of <0.0001 at all times (Table 2 ).

The model was highly significant (Chi-Square = 264.87 (12), p < 0001) and accurately placed 81.6% of the sample into their respective group (Actives versus Withdrawals).

The reduction in mean plaque scores was also highly significant ( P < 0.0001).

P values were represented as asterisks; p values of <0.05 were considered statistically significant: 0.01–0.05, significant (*); 0.01–0.001, very significant (**); 0.001–0.0001, highly significant (***); p<0.0001, extremely significant (****).