The likelihood of undergoing resection has been shown to decrease with increasing age, with patients of age group 65–69 years having a 71% resection rate compared with 69% for those aged 70–74 years, 62% for those aged 80–84 years, 46% for those aged 80–84 years, and 31% for those aged 85 years and older, which was highly significant ( P <0.0001) even after adjusting for confounding factors. 3 This same trend was repeated almost identically for receipt of RT within 3 months of diagnosis or receipt of chemotherapy within 3 months of diagnosis, when analyzed according to increasing age, in the same US population-based report, 3 a
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From Table 9 , it is evident that the model is highly significant ( P < 0.0001), while the lack-of-fit term is not significant ( P > 0.05).
The ANOVA analysis showed a highly significant difference (DF = 2, p < 0.0001) in mortality of D. opuntiae nymphs 4 days after the spray.
However, the associated MANOVA was highly significant (Wilk's lambda = 0.0183; df = 176, 8545; p<0.0001) and in pairwise Hotelling's comparisons (with four constraints) all MOTUs could be distinguished from each other (p<0.0001 in all cases).
65,66 Statistical analysis confirmed these reductions were highly significant ( p < 0.0001) compared with the EAC control.
Linear regression analysis revealed a highly significant positive correlation ( r = 0.2426, P < 0.0001).
The Satorra–Bentler scaled χ 2 difference test was highly significant (Δχ 2 (21)= 1250, p <.0001), with ΔCFI = –.14 and ΔRMSEA = +.035, both exceeding recommended thresholds for meaningful deterioration in fit (Cheung & Rensvold, 2002; Chen, 2007).
Similarly, the percentages of antigen-experienced CD4 + T cells subsets that could be identified as specific CD4 T cell subsets in AIT-treated asthmatic mice showed highly significant increases in T H 1 ( p < 0.0001) and T H 17 ( p < 0.01) cells, while decreases were noted for antigen-experienced CD4 + T H 2 ( p < 0.0001) and Treg cells ( p < 0.0001) compared to the asthmatic mice ( Figure S5-c ).
Intragroup reductions from baseline remained highly significant at all time points in both groups (p = 0.0001).
Longitudinal tumor growth data, analyzed using a linear mixed-effects model with restricted maximum likelihood, revealed highly significant effects for both the time × group interaction [ p < 0.0001, F(5.514, 32.81) = 11.36] and the group main effect [ p < 0.0001, F(5, 119) = 41.56] ( Figure 2e ).
As expected, only very minor differences were noted between the antibodies with and without LS (Table 1 , Suppl Table S1 A,B), with highly significant correlation between values: for each pair of antibodies, both IC50 values and IC80 values correlated with Spearman’s rho of 0.94 or higher and p < 0.0001; and the median IC50s were no more than twofold different, which is within experimental error for this assay 17 .
Moreover, 8 classes, including CE, CER, DAG, FFA, LPC, PC, SM, and TAG, showed highly significant differentiation with p -values < 0.0001 ( Table 1 ).
Concerning p -values, the results were highly significant for the protein when stored at 4 °C for all the tested conditions ( p -value < 0.0001), and significant when the protein was stored at −80 °C ( p -value < 0.05 and p -value < 0.01).
We examined the socio-demographic elements that affect people’s awareness of the osteoporosis condition, and we found that there is a highly significant correlation between work environment and osteoporosis knowledge (p-value = 0.0001).
Except for lung cancer, there are strong and highly significant trends of increasing cancer risk with increasing height ( P < 0.0001 for colorectal cancer, malignant melanoma, breast cancer, ovarian cancer, and other cancers and P = 0.002 for non-Hodgkin lymphoma).
Differences in interactions among genotypes, different points in the time-course and the presence or absence of pathogens were highly significant ( p < 0.0001).
Regression analysis showed that shortness of breath was a highly significant ( P <0.0001) predictor of impact items.
The difference in mean value of insulin dose (MID) showed a highly significant decrease ( P <0.0001) from baseline to end of the treatment i.e. from 36.26 ± 18.21 to 26.87 ± 16.49 IU.
The multivariate logistic regression model was highly significant ( p < 0.0001, R2 = 0.54) and showed that all these factors were independent in predicting mortality of sepsis.
Kaplan Meier analysis (Figure 3 a) showed the difference in DSS between risk groups to be highly significant (P = 0.0001, HR: 2.23 95 % CI: 1.46 to 3.50).
Conversely, the treatment caused a highly significant ( p < 0.0001) decrease in Pol, Tax, and HBZ expression with respect to the untreated control in PB2/NO-IL-2 cells.
For all pulmonary function test parameters [forced expiratory volume in 1 second (FEV 1 ), forced vital capacity (FVC), FEV 1 /FVC, and forced expiratory flow (FEF (25-75) )] a highly significant (p < 0.0001) reduction of the values was observed in biomass users.
Changes in overall cell growth did not reach significance after ADAM10 single knockdown ( Figure 4 a,b) being, however, highly significant after ADAM17 knockdown ( p = 0.0001; Figure 4 c,d) and to a lesser extend also following ADAM10/17 double knockdown ( p = 0.0012 and p = 0.0027; Figure 4 e,f).
However, comparing adherence trends in the subsamples with comorbid ADHD (n = 117) and without ADHD (n = 62) showed that the association between younger age and poor adherence was highly significant in the subsample with ADHD (OR = 0.57, 95% CI 0.45-0.73, p < .0001) and nonsignificant in the subsample without ADHD (OR = 1.08, 95% CI 0.80-1.47, p = .6).
The random effects model indicated a significant mean difference (MD) of -1.66 (95% CI: -2.39 to -0.93), with a highly significant p-value of <0.0001, suggesting a substantial reduction in abdominal pain due to probiotic treatment.