Barely Significant

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highly significantp < 0.00010.0× alphaqualifiedgold
Comparison of change in mean size of the lesion within group A and group B at 4 weeks Within-group analysis for Group A showed a highly significant reduction in lesion size from baseline (Figure 4 ) to the four-week endpoint (Figure 5 ), with a mean score change of 2.0+/- 0.95 (t = 8.16, df = 11, p < 0.0001).
highly significantp < 0.00010.0× alphaqualifiedgold
After imputing missing studies in the funnel plot, adjustment of effect size for possible publication bias using the trim-and-fill correction results in decreased, albeit still highly significant estimate of pooled mean difference (adjusted = −0.36 logMAR; 95% CI: −0.44; −0.28; p < 0.0001).
highly significantP < 0.00010.0× alphaqualifiedgold
In the active rTMS group, the mean number of correct answers on the PRM test increased by 4.54 ± 2.98 from baseline to week 8, while the correct number in the sham group decreased slightly (-0.92 ± 2.72) and the difference between these changes was highly significant (mean 5.46 ± 0.92, 95%CI: 3.43–7.14, F = 33.3, df = 137, P < 0.0001, effect size = 0.474) (Table 2 ).
highly significantp < 0.00010.0× alphaqualifiedgold
The correlation between food items/categories and ITMI was positive and highly significant ( p < 0.0001, except for dairy p < 0.01) for pasta, vegetables, fruit, legumes, fish, EVOO, and dairy products; while it was negative and significant for potato, butter, soft drinks, red/cured meat, and sweets with Pearson’s coefficients ranging from 0.10 (dairy) to 0.49 (vegetables) and from −0.20 (potato) to −0.41 (soft drinks) for positive and negative correlations, respectively.
highly significantP < 0.00010.0× alphaqualifiedgold
There were highly significant differences in the change in HbA 1c between each alogliptin combination group and the glimepiride monotherapy group ( P < 0.0001), whilst the different dosages of alogliptin produced similar reductions in HbA 1c .
highly significantp < 0.00010.0× alphaqualifiedgold
When comparing this time span between both study groups we found a highly significant reduction in diagnosis-to-treatment time in the intervention group compared with the control group ( p < 0.0001; Fig. 3 a) with a mean time span of 14 days for the intervention group and 36 days for the control group and with a range between 7 and 81 days.
highly significantP < 0.00010.0× alphaqualifiedgold
The most dramatic impact was recorded in the thymus, where a sharp decline in weight was evident as early as 3 dpi (0.13 ± 0.00 g) compared to the control (0.32 ± 0.01 g), maintaining a highly significant atrophy throughout the 35-day period (P < 0.0001).
highly significantp < 0.00010.0× alphaqualifiedgold
However, during the second and third weeks, animals maintained at 21°C consumed on average 21.5% more than animals housed at 32°C, but despite this highly significant difference in ingested food ( p < 0.0001), only the warmed animals gained a significantly greater amount of weight.