Conversely, as found for bottlenose dolphins ( Williams et al., 2017b ), there were highly significant relationships between V̇ O 2 ss (J kg −1 min −1 ) and f S (strokes min −1 ) ( n =30 swims, d.f.=1, 28, F =25.53, P <0.0001, AICc=304.28, BIC=308.29; Fig. 4A ) for beluga whales, where: (1) and between V̇ O 2 ss (J kg −1 min −1 ) and swim speed ( U swim , m s −1 ) ( n= 30 swims, d.f.=1, 28, F =54.93, P <0.0001, AICc=288.48, BIC=291.76; Fig. 4B ), where: (2) even within the relatively narrow range of exercise efforts representing the preferred performance levels of the individual whales.
Excerpts
Adjusted means showed the same stepwise increase (77.1, 85.4, and 89.4 fL, respectively), with all pairwise contrasts being highly significant (p ≤ 0.0001).
The mixed-effects model analysis indicates highly significant effects of time, treatment groups, and their interaction on hepatocyte viability ( p < 0.0001 for all).
When it comes to lRFS the Rome classification showed highly significant predictive value (p<0.0001 both at Log-Rank and Wilcoxon) with a notable progressively lower local control for each increasing T stage.
The estimation of the variance component showed a highly significant behavior ( p < 0.0001) of the genotypes and the genotype x environment interaction across all the environments.
However, we noted a 20-fold increase in the frequency of H2AX −/− bouquet-stage nuclei ( H2AX −/− , 6%; wild-type, 0.4%; based on 2,567 mutant and 2,772 wild-type spermatogenic nuclei), with the differences being highly significant (P < 0.0001; χ 2 and Fisher test; Fig. 2 B).
As shown in Table S10 , the model had F = 10.65 and was highly significant ( p < 0.0001), while the lack of fit was not significant ( p = 0.0652 > 0.05).
The prevalence of highly significant comparisons (**** p < 0.0001) indicates that changes in the storage modulus were strongly formulation-dependent, validating the ability to decouple and reproducibly control hydrogel mechanical properties through polymer design.
Primary Efficacy Endpoint Most Bothersome VVA Symptom Highly significant (p<0.0001, See Table 1 ) improvements from baseline at both 4 weeks and 12 weeks follow-up for the most bothersome VVA symptom, of which dyspareunia and vaginal dryness were the most frequently occurring, were noted in both groups.
The AHI showed the most prominent group difference (Wilcoxon-Kruskal-Wallis rank sum test was highly significant with chi 2 = 22, df = 3 p < 0.0001) with severely lower event rates in the LTG (9.45/h) compared to POAG (22.7/h) and controls (21.9/h; p < 0.0001 and 0.02, respectively).
Sexual selection against hybrid males For pooled values, the pairing success rate for male Golden‐winged Warblers was 83% and for male Brewster's Warblers was 54% (Table 3 ), a highly significant difference ( χ 2 = 44.35, p < .0001).
Analysis of 2,331,175 unique patients tested March-May 2020 demonstrated an increasing trend in SARS-CoV-2 NAAT positivity across Black non-Hispanic community progressive quintiles (from 7.8% to 17.2%, P < 0.0001) and Hispanic community progressive quintiles (from 8.4% to 15.5%, P < 0.0001) and a decreasing trend across White non-Hispanic community progressive quintiles (from 17.4% to 7.1%, P < 0.0001).
The analysis of variance of phenotypic data revealed a highly significant effect of the genotype ( P < 0.0001) on the disease incidence, with no significant differences observed between replications ( P = 0.38).
In addition, when comparing delta values of both groups, we observed in MTZ-treated patients a highly significant reduction (i.e., clinical improvement) for both RCSS ( p < 0.0001, Mann-Whitney; Fig. 4 b) and MBAS values ( p < 0.0001, Mann-Whitney; Fig. 4 d) with respect to the untreated group.
Interestingly, our formulation was capable of inducing a 1.65-fold higher immune response in rabbits than in cattle (i.e., a 65% increase); this difference was highly significant (p<0.0001; Figure-3a and b ).
Results There was an extremely significant (p < 0.0001) reduction in body weight (108.62 kg→ 94.48 kg), body mass index (36.46 kg/m 2 →31.76 kg/m 2 ), systolic blood pressure (125.71 mmHg→109.05 mmHg), diastolic blood pressure (84.52 mmHg→ 75.24 mmHg), total cholesterol (208.24 mg/dl→186.62 mg/dl), triacylglicerols (218.67 mg/dl→113.90 mg/dl) and glucose (109.81 mg/dl→ 93.33 mg/dl).
These observations were statistically validated with a Kruskal-Wallis H test, which showed a highly significant result (P < 0.0001), confirming that the medians of the ratios differed significantly across the four phases.
This finding conforms to the results of the present study, mainly, for the winter season as the difference in classification accuracy between two models was +32.2 with highly significant at p -value < 0.0001 using paired t -test.
The correlation between the mean fixation duration in session 1 and session 2 was highly significant, r = 0.82, p < 0.0001, replicating previous studies ( Guy et al., 2019 ; Henderson & Luke, 2014 ).
The suppression was dose dependent for anti-rTsSerp antibodies ( r = 0.986) and showed a decreasing trend with increasing serum dilutions ( F = 181.170, P < 0.0001) (Figure 10 F).
Notably, Rad-scores derived from wavelet, LoG, and combined feature classes all demonstrated highly significant p ( p < 0.0001), indicating a stronger association between Rad-scores and OS in GBM patients.
The mean severity of glistening based on subjective assessment was 0.57 ± 0.60 in the Z-Flex, and 1.82 ± 0.90 in the Acrysof IQ group, and the difference was highly significant (p<0.0001).
Furthermore, the graphical analysis highlighted an increasing trend in the metabolically active viable cell population, dependent on the number of CAP applications ( p < 0.0001).
However, a highly significant and strong correlation ( p < 0.0001) was found between the number of nuclei per OC and the percent eroded surface per bone surface in vitro ( Figure 4 b).
Adhesion Protocol Comparisons In comparisons of different adhesion protocol groups for each RBC, there were highly significant differences between and among groups for all RBCs: FOBF ( F =266.87, P <0.0001), TNCBF ( F =173.16, P <0.0001), and Z350XT ( F =103.64, P <0.0001).