Barely Significant

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highly significantp < 0.00010.0× alphaqualifiedgold
The same conclusion was reached by a study conducted in Guatemala on the link between the nutritional status of children with cancer and socioeconomic status, which showed that SES was associated with the nutritional status of children with cancer, the lower the SES, the greater the nutritional vulnerability, with a highly significant association ( p < 0.0001) ( 32 ).
highly significantP < 0.00010.0× alphaqualifiedgold
Statistical analyses of absolute abundance values showed that 17 of the top-30 differential metabolites by importance were significantly upregulated in the CMPLXL group versus the CMPLXH group compared with the MOD group, and 13 of these differences were highly significant (P < 0.0001) in both comparison groups.
moderately significantP < 1 × 10 −40.0× alphaqualifiedgold
To further validate our findings in the proteome-wide cis -MR, we applied gIVW by including moderately significant ( P < 1 × 10 −4 ) and correlated (r 2 < 0.4) cis-pQTLs as instruments. 34 Out of the 53 associations of lipid fractions with plasma proteins, gIVW produced consistent and statistically significant estimates (Prange = 1.1 × 10 −28 to 0.05) for 43 associations ( Supplementary Table S5A ).
a significant trendp < 0.00010.0× alphagold
In males, the odds ratios (ORs) for hyperuricemia across increasing quintiles of retinol intake were 1.13 (95% CI: 0.81–1.58), 0.87 (95% CI: 0.62–1.22), 1.59 (95% CI: 1.17–2.16), and 2.31 (95% CI: 1.72–3.12), respectively, compared to the lowest quintile, with a significant trend ( p < 0.0001) in the fully adjusted model.