Excerpts

Only the main effect of germination conditions was highly significant (F (2, 51) = 17.952, p = 1.25e-06).

The genotype‐by‐density interaction was highly significant, indicated by both the chi‐square test (ΔAIC = 7, p = 1.25E‐06; Table 2 ) and the crossover reaction norms in Figure 2 , with 7.6% of the genetic variance being due to this interaction effect.

The difference was highly significant ( P = 1.28x10 -6 ).

The correlation was highly significant with the correlation coefficient rs = − 0.07, p = 0.00000129 (Fig. 1 ).

When combining samples carrying the four co-susceptibility alleles A29, A30, A31, and A33, we found a highly significant enrichment in BSCR cases when compared with the larger control cohorts (GHS cohort 1, P = 1.29E-06; GHS cohort 2, P = 1.07E-06; UKB, P = 9.62E-07) ( Table 1 , top row).

Incorporating domain specific feature extraction further improves its performance to an AUC of 0.855, which is highly significant (p = 1.3E-06).

Non-parametric comparison of median MOR between these two groups showed highly significant differences (p < 1.3 × 10 −6 ) (see Supplementary Table S5 ).

Within the Detected group, the difference between global methylation levels in PLWH and SN was highly significant at Visit 2 (post-HAART, p = 1.3 × 10 −6 ; Welch’s t -test comparing mean CpG values in each PLWH group to their matched SN controls), while within the Undetected group, the mean difference in global methylation between PLWH and SN and the significance ( p = 0.015) were diminished. 3.3 GREAT functio

At the end of the study (165 days), after three dosing cycles of E5, we observed highly significant improvements in TNF-alpha levels (Student’s T test p = 1.3 × 10 −6 for males and p = 7.6 × 10 −5 for females) and IL-6 levels ( p = 4.1 × 10 −6 for males, p = 3.4 × 10 −6 for females, Supplementary Fig. 14 A–D) in the blood of E5-injected rats over that of saline controls.

This is a highly significant ( P = 1.3 × 10 −6 ) 26-fold enrichment when compared to randomly selected genes.

p -values for most porphyrins were highly significant (uroporphyrins p = 1.3 × 10 −6 , pentaporphyrins p = 9.21 × 10 −8 , total porphyrins p = 2.61 × 10 −5 ) when comparing the youngest (≤5 years) and oldest (>10 years) age groups.

In contrast, the difference in paternal repeat expansion between pure an interrupted repeats was highly significant (Fig. 4B ; p = 1.3E–6; Fisher’s Exact test).

SNP associations were genome-wide significant with CC-BNT (P<2.4×10 −7 ) and CC-WRAT (P<1.0×10 −8 ), nearly genome wide significant with CC-LMI (P<6.0×10 −7 ), and highly significant with CC-LMD (P<1.3×10 −6 ), CC-HVOT (P<1.9×10 −6 ) and CC-TMTB (P<3.7×10 −6 ).

Quantification shows controls have 7.8 ± 1.0 projections/bend whereas dfmr1 nulls have 17.8 ± 1.2, a highly significant elevation ( p = 1.3 × 10 −6 , two-tailed unpaired t test; Fig. 3 b, left).

Highly significant differences between both Andean wild and Andean domesticated accessions ( p-value = 1.314e-06, Wilcoxon test) and between Mesoamerican wild and Mesoamerican domesticated accessions ( p-value = 0.011, Wilcoxon test) were observed.

However, there was a highly significant difference in rank changes between the MSR and FSM management regimes (P = 0.00000132, Welch’s T Test, Two-tailed).

By contrast, there was a strong and highly significant association between genodermatosis subtypes and inheritance pattern ( p = 0.0000013378; adjusted p =0.0000053512; Cramér’s V = 1.000) ( Table 3 ).

BMI is also strongly correlated with SES ( Figure 2 ) but the association of BMI with disease remains highly significant even after accounting for SES and ancestry ( c BMI = 0.09241, P = 1.34 × 10 −6 ).

Only one patient in the cohort predicted not to recur (n = 8) experienced biochemical recurrence 126 weeks post-prostatectomy, a highly significant result (p= 1.38×10 -6 , log-rank test).

In contrast, the internal DNA reads did not follow a normal distribution, with a distinct group of over-represented, or enriched bins which was highly significant (p = 1.382 × 10 −6 ; Fig. 4e,f ).

Overall paired comparisons across the five irradiation scenarios demonstrated highly significant differences for both the mean blood dose and the mean circulating lymphocyte dose (Friedman test: χ 2 = 646.4 , p < 1.39 × 10 − 6 and χ 2 = 638.8 , p < 6.30 × 10 − 6 , respectively) (Data Supplement).

These differences were highly significant for both Proteobacteria and Firmicutes (paired t -tests P = 1.4 × 10 −6 and P = 8.4 × 10 −6 , respectively).

Variance analysis of the response surface revealed that the significance of the TFC was influenced by the percentage of ethanol, which was extremely significant ( p < 0.0000014).

Using Table 6 of that publication, it is possible to calculate the association of lupus anticoagulant (LA) with FVL both in women with recurrent pregnancy loss and in controls, and this association was highly significant for both groups (χ 2 test, P = 1.4 × 10 -6 , for the combined groups: 26 LA-positive women out of 43 women with FVL, compared with 46 LA-positive women out of 209 controls).

This effect remained highly significant when excluding three outlying cases with the strongest coefficients ( β : M = −0.09, SD = = 0.05; t = −7.44, p = 1.41e-06).