M8) were highly significant (all p < 10−8; Table 3 ), with models M2a and M8 estimating that ~ 4.1% of codons evolve under positive selection (ω ≈ 2.31).
Excerpts
The univariate ANCOVA model applied (equation 2 ) revealed very highly significant differences between (1) the culinary oils investigated ( p < 10 −8 , with the exception of cis -2-alkenals for which p = 4.85 × 10 −3 ), and (2) sampling time-points ( p < 10 −8 ) for all aldehydes monitored.
Most regions demonstrated significant heritability contributions to KC, particularly chr8:79,756,170–81,340,231, which exhibited highly significant h2 across KC, AD, AC, and AA (all P < 1 × 10−8).
The role of recombination in mixing the genetic pool of HCMV at the whole genome level is confirmed by a highly significant rejection of the pairwise homoplasy index (PHI) test ( Bruen et al. 2006 ; P < 10 − 8 ).
Furthermore, we found a highly significant correlation (Spearman’s r = 0.76; p < 0.00000001) between uC5b-9/uCre and tissue glomerular C3 fragment deposition, measured by anti-C3 fragment immunostaining ( Figure S13 B), suggesting that uC5b-9/uCre is a urine biomarker of kidney tissue complement activation.
4b and Supplementary Data 2 ), which is highly significant (Binomial Test P -value < 10 −8 ) and suggestive of their functional importance.
All of the heritability and correlation estimates were highly significant ( p < 1 × 10 −8 ).
Serum levels of 10 biomarkers correlated (r > 0.2, P < 0.05) with the level of fT4 and 12 with the level of TRAb (Supplementary Table). Six biomarkers showed a highly significant increase ( P < 1 × 10 −8 ) between patients with GD and HS ( Fig. 2 ), most significant for TNF receptor superfamily member 9 (TNFRSF9).
The difference is highly significant across repeated experiments with different set of random inputs ( p < 10 −8 , n = 10, paired t -test).
When combining our results across all seven taxa, we found that the overall pattern–i.e., more highly interconnected hub genes exhibited stronger evolutionary constraint–was highly significant (Fisher’s combined probability test, P < 1E-08 for both dN and ω [using CombinePValue; https://CRAN.R-project.org/package=CombinePValue ]; S2 Appendix ).
In this analysis, 263 p53 target genes were co-bound by JMJD3, which gives a highly significant overlap between JMJD3 and p53 target genes (p<10 −8 ).
The results show also a highly significant p value for vessel diameter in the DCP in SWS patients compared to controls ( p = 0.00000001) ( Table 2 ).
Pearson correlation coefficient between replicate transfections was highly significant, reaching 0.88 ( P < 10 −8 ); however, the overall correlation between exogenous and endogenous NSE levels was only 0.35 ( P < 0.01).
Statistical tests showed that the covariance was highly significant in all of the species (Spearman test; P <10 −8 ).
Indeed, Pearson correlation between E2F1 and CCND1 is close to 0 and not statistically significant ( P = 0.4) while the MI is highly significant ( P = 10 − 8 ).
We observed a highly significant main effect of waveform class on decoding performance for each motor feature (median improvement in R 2 was 0.15 across datasets/motor features; p < 1e-8 for every dataset/motor feature combination, Bonferroni adjusted for multiple comparisons).
This result was highly significant (χ 2 = 33.68, p = 1E-8), with 52/166 (31.3 %) genes detected by proteomics showing increased expression in PD, compared with 518/929 (55.7 %) genes not detected by proteomics showing increased expression in PD.
In contrast, HGP treatment induced a highly significant increase in WISP2 expression ( P < 10 −8 ) [ 40 ], but reduced IMF deposition [ 17 ], the opposite of what would be predicted based on the analysis of expression of WISP2 and the IMF 5 gene set genes in WxH and PxH genotype animals.
This test also shows that the difference between AI and human text is highly significant (− log 10 (p)≈8, p ≈ 3.69 × 10−9), and it is due to AI text often having less variety in its vocabulary.
A highly significant relationship was observed between cytokinin dose and GUS activity ( n =119, F =37.99, P =1.02 × 10 −8 , R 2 =0.24) ( Figure 6C ).
This overlap between FMCD genes and the cilia disassembly pathway identified here is highly significant ( P = 1.06 × 10 −8 , Fisher’s exact test; Fig. 5A ), prompting further investigation.
Of these, 19 were expressed in platelets, and String analysis showed a highly significant PPI enrichment ( p = 1.08e- 08).
A Kruskal-Wallis test showed a highly significant difference in water collection times between the kebeles in both wet season (chi-squared = 40.0, p = 1.1 × 10 −8 ) and dry season (chi-squared = 42.3, p = 3.5 × 10 −9 ) ( Fig. 3 ).
The correlation between lineage and average sperm length for all 33 males was highly significant (r = -0.811, n = 33, t 31 = 7.71, p = 1.1E-8).
As expected, a two-sample t -test performed on these raw data confirmed that there was a very highly significant difference between the mean whole-blood HbA1c levels of these two groups ( p = 1.11 × 10 −8 ), with the T2DM one being much greater.