Barely Significant

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highly significantp = 3.06 × 10 −110.0× alphaqualifiedgold
One-way ANOVA confirmed a highly significant overall difference among the groups ( p = 3.06 × 10 −11 ), and subsequent post hoc comparisons indicated that each decalcification treatment resulted in significantly lower density values than the controls ( p < 0.0001).
highly significantP -value = 3.22E-110.0× alphaqualifiedgold
Highly significant gene ontology (GO) terms were identified for the DPC associated modules including “dendrite morphogenesis” (“blue” module; P -value = 3.22E-11), “negative regulation of synaptic transmission” (“black” module; P -value = 6.29E-09), “negative regulation of axon extension involved in axon guidance” (“red” module; P -value = 3.64E-09) and “embryonic organ morphogenesis” (“green” module, P -value = 1.79E-11), suggesting that the large changes in 5hmC across fetal brain development contribute to the regulation of relevant biological processes.
marginal significanceP -value < 3.5e-110.0× alphagold
Also, ribo-lincRNAs generally exhibited higher GC-content than nonribo-lincRNAs (Mann–Whitney U test, P -value < 0.05; Figure 1H ), except for the BJ and RPE, with marginal significance for the hES and PC3, although lincRNAs typically had lower GC-content than protein-coding genes (Mann–Whitney U test, P -value < 3.5e-11; Supplementary Figure S8B and Table S7 ).
highly significantp = 3.5 × 10 −110.0× alphaqualifiedgold
On the contrary, palmitoleic acid showed several highly significant correlations with anthropometric features (BMI: r = 0.408, p = 3.5 × 10 −11 ; waist/height ratio, fat mass: r = 0.402, p = 3.35 × 10 −10 , fat-free mass) and with systolic (SBP) and diastolic BP (DBP).
highly significantp=3.6x10 -110.0× alphaqualifiedgold
cutoff 0.5: https://www.rdocumentation.org/packages/genefilter/versions/1.54.2/topics/nsFilter This analysis resulted in just 213 unique genes that were differentially-expressed at a nominal p-value<0.05, 35 of which had a fold change in expression >1.5 (the 24 genes from Table 2 as well as Psg25 , 1700047G07Rik , Ugt2b5 , Vmn1r86 , Olfr493 , Olfr295 , Vmn1r37 , Olfr800 and Fpr2 ); for the 213 genes, the KEGG pathway ‘olfactory transduction’ remained highly significant (p=3.6x10 -11 ), as did the GO biological pathway terms ‘G-protein-coupled receptor signalling’ and ‘sensory perception of smell’ (p=7.9x10 -12 and p=1.2x10 -12 respectively) and the GO molecular function terms ‘G-protein coupled receptor activity’ and ‘olfactory receptor activity’ (p=9.6x10 -17 and 2.4x10 -13 respectively).
highly significantP = 3.6 × 10 −110.0× alphaqualifiedgold
When we ran a binary logistic regression analysis with group (LBD versus atypical PS) as a dependent variable and both DDC level and SAA status as independent predictors, we found that SAA was a highly significant variable that discriminated LBD from atypical PS(SAA: β = 5, P = 3.6 × 10 −11 , AUC = 0.95, sensitivity = 0.93, specificity = 0.93), in contrast to DDC ( β = 0.6, P = 0.01, AUC = 0.73, sensitivity = 0.37, specificity = 0.89) (Extended Data Fig. 4a ).