Barely Significant

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marginal significanceP = 0.010.2× alphagold
Although we found marginal significance between two SNPs, rs7013278 and rs7014346 (HR = 2.20, P = 0.01 and HR = 1.96, P = 0.03 respectively), with inferior CRC survival by multivariate regression analysis, none of these variants showed study-wide association with survival after correction for multiple testing.
highly significantp -value < 0.010.2× alphaqualifiedgold
Since the interaction effect of population and extraction method was highly significant ( p -value < 0.01) for all four response variables ( Table 11 ), multiple means comparison was done to compare the nine combinations of population and extraction method using the lsmeans statement at the 5% level of significance ( Table 12 ).