Barely Significant

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an increasing trendP < 0.0010.0× alphagold
Similarly, GPP max_EC-LUE also followed the same pattern with NDVI max , showing an increasing trend from 1982 to 2018 at a rate of 1.13 ± 0.12 × 10 −2 g C m −2 d −1 yr −1 (t (35) = 9.67, P < 0.001, 95% CI [0.89 × 10 −2 , 1.36 × 10 −2 ]), but declining during the 1998-2009 period at a rate of −0.51 ± 0.29 × 10 −2 g C m −2 d −1 yr −1 (t (10) = −1.77, P = 0.11, 95% CI [−1.14 × 10 −2 , 0.13 × 10 −2 ], Supplementary Fig. 2c ).
highly significantp < 0.0010.0× alphaqualifiedgold
Moreover, when we fit a model using daily HEI instead of the regular HEI score (with age and BMI as continuous variables and without any interaction terms), daily HEI remained a highly significant predictor of Shannon entropy ( β = 0.019, p < 0.001, 95% CI [0.0141, 0.0242])) (Supplementary Table 3 ), reflecting an even stronger effect than the standard HEI coefficient would have shown in that same model ( β = 0.013, p < 0.001, 95% CI [0.0085, 0.0179]).
highly significantp < 0.0010.0× alphaqualifiedgold
The agreement between the classification based on both campaigns and each single campaign dataset was highly significant (99.3%, k = 0.991, p < 0.001 for the test, when the Baffin Bay was the training set and the Fram Strait dataset was predicted and 92.9% of agreement, k = 0.905, p < 0.001 when reversed, i.e., Fram Strait as training dataset and the Baffin Bay as predicted).
highly significantp < 0.0010.0× alphaqualifiedgold
Regional Pf prevalence shows a highly significant positive correlation with levels of predicted PPQ-R estimated from the proportions of pm23 amplifications ( R = 0.64, p < 0.001), where periods of lower prevalence were generally characterized by lower PPQ-R proportions, suggesting that switching away from the use of DHA-PPQ as the frontline ACT may have had an impact on prevalence (Supplementary Fig. 6 ).
highly significantp < 0.0010.0× alphaqualifiedgold
We found a highly significant, positive interaction (p < 0.001) effect between MAPK-pathway altered diffuse low-grade gliomas relative and clusters 1 and 2 (Fig. 3F , Supplementary Fig. 4 ), indicating over-representation of tumors with a higher expression of immune infiltrate-related genes with this tumor entity.
highly significantp = 0.0010.0× alphaqualifiedgold
4C becoming highly significant (both increasing vs increasing-decreasing p = 0.001; both increasing vs other p = 0.013; both decreasing vs increasing-decreasing p < 0.001; both decreasing vs other p < 0.001; LME post-hoc tests, Tukey correction), as well as the difference between increasing-decreasing and other pairs becoming significant ( p = 0.040).
highly significantP < 0.0010.0× alphaqualifiedgold
By using linear mixed model analyses testing for genetic variation among accessions, and by estimating the impact of the TM treatment on biomass accumulation compared to the respective mock control, we detected a highly significant accession-by-treatment interaction ( P < 0.001), highlighting natural variation in the accumulation of biomass of the accessions in response to chronic ER stress.