Excerpts

Specifically for Northern Europe, there is a marginally significant ( P =0.06) warming despite a highly significant ( P <0.001) decrease in zonal wind ( Table 1 ), the latter implying a more easterly flow regime typically linked to colder winter temperatures.

These tests were considered not significant when p ≥ 0.05 (ns), significant when 0.01 ≤ p < 0.05 (*), very significant when 0.001 ≤ p < 0.01 (**), and extremely significant when 0.0001 ≤ p < 0.001 (***) or when p < 0.0001 (****).

Data from six animals revealed mean peak MRI signal changes of 5.3±0.9% during wtCGRP injection, compared with changes of 1.2±0.1% during injection of aCSF alone; the difference between wtCGRP and vehicle was highly significant ( t -test P =0.001).

1D to a logistic Binomial regression model showed a highly significant effect of hpi (χ 2 = 132.964, 2 d.f., P < 0.001), mostly driven by the very low infectivity observed 36 hpi.

001, see also the highly significant clip-type × movement-type interaction ( F (1,13)=105.8, P <0.001, all post hoc tests P values <0.001): this shows that during correction-power grips, participants were truly performing a movement correction, changing trajectory from a higher (that is, precision grip position) to a lower one (that is, power grip position) during the reaching phase.

This difference is highly significant compared to all other individual time intervals ( P < 0.001; N = 136; two-sided heteroscedastic Student ́s T -test).

The bias towards the shortest chromosomes is highly significant, P = 0.001.

Between lactation days 1 to 15 there was a highly significant effect of day of lactation (RM GLM F = 35.18, P < 0.001) as well as a significant effect of diet ( F = 5.134, P = 0.041) on maternal gross FI.

Statistical analyses were performed using a two-tail Fisher-exact test: P -values ≤ 5.00e-2 (a = 0.05) were taken to be significant (1.00e-2 ≤ P ≤ 5.00e-2 * significant; 1.00e-3 ≤ P ≤ 1.00e-2 ** very significant; P < 1.00e-3 *** highly significant).

In contrast to the highly significant ( P < 0.001) ANO1 current reduction (Fig. 4a ), SR Ca 2+ release was indistinguishable ( P > 0.05) from control scrambled siRNA expressing myotubes (Fig. 4b ), indicating that the observed ANO1 current reduction cannot be attributed to putative siRNA off-target effects hampering SR Ca 2+ release.

Differences were considered significant at * p < 0.05 and ** p < 0.01 or were considered highly significant at *** p < 0.001.

When compared to the 3373 common targets of three B-ARRs, the percentage of overlap dropped to 35.4% which is still highly significant (Fig. 4b ; Fisher’s Exact Test p < 0.001).

We removed SNPs from the meta-analysis if they exhibited highly significant heterogeneity across studies (Cochran Q I 2 P -value ≤ 0.001), or co-located with CpG from the DNAm age predictors according to the Illumina annotation file for the Illumina Infinium 450K array.

Log-rank test confirmed a highly significant difference between the two groups ( p < 0.001) demonstrating clear separation of survival trajectories.

4C becoming highly significant (both increasing vs increasing-decreasing p = 0.001; both increasing vs other p = 0.013; both decreasing vs increasing-decreasing p < 0.001; both decreasing vs other p < 0.001; LME post-hoc tests, Tukey correction), as well as the difference between increasing-decreasing and other pairs becoming significant ( p = 0.040).

The model can make predictions of the WNP TC density averaged over the WNP (0°–60°N,100°E–180°) during June–August, which corresponds to the first half of the WNP TC season 34 , with a highly significant skill ( r = 0.67, p < 0.001) for the first summer (Fig. 5a ) and a moderate skill ( r = 0.39, p = 0.017) for the second summer (Fig. 5b ).

There was a highly significant tendency of the BV-positive samples to sort to the polymicrobial clade and BV negative samples to the Lactobacillus clade based on either the Amsel ( p < 0.001) or Nugent BV diagnosis ( p < 0.001).

The lower prevalence of parasitism in the naïve catfish treatment was highly significant (Generalised Linear Mixed Model (GLMM) with binomial error distribution, n = 509 host clutches; naïve vs. experienced catfish: z = 4.31, P < 0.001; naïve vs. highly experienced catfish: z = 3.60, P < 0.001), but the probability of parasitising cichlid clutches did not differ between experienced and highly experienced catfish ( z = 0.75, P = 0.452) (Supplementary Table 2 ).

We find that the increase in tubule density in the presence of dimerizer is highly significant ( p < 0.001), and there is a strong trend toward increased tubule complexity ( p = 0.09).

This result, that G-specific TAD borders were frequently positioned at G-specific compartment borders, was highly significant ( P < 0.001, two-sided Mann–Whitney U test; Fig. 5c ).

The significance thresholds were deemed as statistically significant ( P ≤0.05), highly significant ( P ≤0.01) or extremely significant ( P ≤0.001).

The results of the present study revealed an increasing trend in juniper growth with decreasing sea ice extent ( r = −0.59, 1901–2015, p < 0.001), particularly during notable recurrent periods of significant ice cover increases in 1907, 1935–1936, 1983–1984 and 2008, resulting in low growth.

hepatica , proxies of six variables found to be significant in previous studies 6 , 7 were highly significant (all p < 0.001), as was herd size (p < 0.001).

Supporting the notion of trait-like stability in sAA, we observed highly significant medium- and large-sized correlations in baseline sAA between the 3 days (day 1–2: R(51) = 0.46, p < 0.001; day 1–3: R(51) = 0.61, p < 0.001; day 2–3: R(51) = 0.60, p < 0.001; n = 53; Supplementary Fig. 4a–c ).

4a ) indeed exhibits an increasing trend with the latitude ( r = 0.27, P < 0.001), suggesting a certain association with IGWs.