Barely Significant

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Ligand Fitting: Differences on the Electrostatic Distribution, Water Activity and Stereochemical Adjustments Around the Active Sites of Hibg and Aabg and Ligand Dynamics The APBS and GIST analyses of the decoys recovered from the MD FELs ( Figure 2 ) show a high negative electrostatic potential as well a significant trend to favorable water retention at the catalytic cleft of both enzymes ( Figure 4 A,B,D).
Compared with the MG, UA and creatinine serum concentrations were decreased in all treatment groups, especially in the AP group (APG) ( P < 0.01) and EDG-50 group (50G) ( P < 0.05); creatinine and blood urea nitrogen concentrations in the APG were significantly increased ( P < 0.01); EDG extracts with different polarity reduced creatinine and blood urea nitrogen, which was slightly significant in the 50G, but not significantly different in the MG.