Excerpts

Highly significant decreases in the relative risk for myocardial infarction are shown for PM 2.5 and PM 10 , for NO 2 , NOx and SO 2 and for CO at higher concentrations ( p < 0.01 for all pollutants).

The study was terminated early since the planned interim analysis showed a highly significant reduction in RBC transfusion with a p -value < 0.01 according to predefined conditions.

Statistically significant improvements were noted at as early as month 3 ( p = 0.02), with highly significant gains by month 6 ( p < 0.01), which remained stable through month 12 ( p < 0.01).

The differences between delivery and all subsequent time points were statistically highly significant (adjusted p -value < 0.01).

However, a positive and strongly significant correlation was found between inflammatory cell count and neovascularization scores (r = 0.708, p < 0.01), and a positive and moderately significant correlation was found between new bone formation and neovascularization scores (r = 0.535, p < 0.01).

In the HF group (59 patients), PWV demonstrated a positive moderately significant correlation with creatinine ( r = 0.33; p = 0.01), RDW ( r = 0.31; p = 0.02); NT-proBNP ( r = 0.28; p = 0.049), brachial SP ( r = 0.33; p = 0.01), central SP ( r = 0.29; p = 0.02), and a negative moderately significant correlation with eGFR ( r = −0.40; p = 0.002) ( Figure 1 ).

Staining results revealed a significant trend of higher expression of ATP5E in tumor tissues compared to normal tissues ( Figure 1 e,f, p < 0.01).

The correlation between index and last referral was moderate ( r = 0.51) and highly significant ( p < 0.01).

The young and elderly showed a decreasing trend in the first 3 days ( p < 0.01), returning close to baseline levels by day 5.

When pooled across studies, TMB-high compared with TMB-low showed a trend toward improved PFS (pooled HR 0.47, 95% CI 0.33–0.7, p < 0.01).

All tests were two-sided and differences were considered to be significant when p < 0.05 and highly significant when p < 0.01 in all cases. 3.

All lung function parameters with a highly significant difference ( p < 0.01) between PH patients and healthy controls in univariate analysis were included in a stepwise generalized linear model.

Differences were statistically significant if p < 0.05 and highly significant when p < 0.01.

When patients were split into 10 patients with an initial MELD score of >10 and 10 patients with an initial MELD score of ≤10, nine parameters showed a highly significant ( p < 0.01) difference between these two groups ( Table 2 (middle part)) and seven other parameters had a significant ( p < 0.05) difference (not presented).

A comparison of the median values using a one-way Kruskal–Wallis analysis of variance showed highly significant differences in the speech activity (% PET, H = 9.166, p = 0.010), CARS score (H = 16.209, p = 0.0003) and SNAP-IV score (H = 10.148, p = 0.006) during the six month follow-up period. 3.4.

Correlation Analysis of Two-Dimensional CPs to Three-Dimensional SASN Correlation analysis revealed strong, statistically highly significant correlations between A min and the two-dimensional respiratory parameters SPAS (r = 0.706; p < 0.01), MPAS (r = 0.713; p < 0.01), and IPAS (r = 0.684; p < 0.01), as well as the three-dimensional parameters V PAS (r = 0.857; p < 0.01), A Sag (r = 0.708; p < 0.01), A SPAS (r = 0.812; p < 0.01), A MPAS (r = 0.888; p < 0.01), and A IAS (r = 0.835; p < 0.01; Table 4 ).

Statistical differences were considered significant when p < 0.05 (*), and highly significant when p < 0.01 (**), as reported elsewhere in similar studies [ 43 , 47 ]. 3.

Within the breathing control subgroup, gastroesophageal reflux disease questionnaire (GERDQ) scores showed a trend favoring the abdominal breathing regimen (SMD = −0.74; 95% CI: −2.06 to 0.57), though this did not reach statistical significance, and heterogeneity remained high ( I 2 = 85.9%, p < 0.01).

For highly significant findings, p -values < 0.01 were additionally reported. 3.

A highly significant association ( p < 0.01) in the prevalence of K. pneumoniae in different units was found.

Notably, the differences in resonance frequencies remained highly significant even after adjusting for age ( p = 0.01 for the right ear, p = 0.001 for the left ear; Figure 1 ), and low-frequency absorbances at 0.25, 0.5 and 1 kHz also remained highly significant ( p < 0.05), confirming that the findings were independently associated with NAFLD status rather than age variance. 3.3.

IL-6 concentrations above the cut-off value of 100 ng/L showed statistically highly significant associations with neonatal sepsis in chi-square tests: CP EOS (OR = 6.307, 95% CI: 1.314–29.666, p = 0.011), clinical EOS (OR = 7.093, 95% CI: 4.238–11.873, p < 0.001), CP LOS (OR = 14.37, 95% CI: 6.095–33.881, p < 0.001) and clinical LOS (OR = 33.526, 95% CI: 12.521–89.770, p < 0.001).

Sensitivity Analyses (1) In patients with complete SUA data, we also found a reduced risk of AMI associated with lower SUA levels among allopurinol current users (AOR <6 mg/dL = 0.70; 95% CI: 0.53–0.91; AOR 6–7 mg/dL = 0.88; 95%CI:0.63–1.24; AOR >7 mg/dL = 1.03; 95%CI:0.76–1.40) showing a significant trend ( p = 0.011) ( Table 3 ); (2) the exclusion of hypertension from the adjusted model had no impact in the AOR estimates. 4.

Moreover, we observed a significant trend towards a decline in urine phosphate excretion, visible as early as the third month of treatment (0.53 ± 0.18 vs. 0.44 ± 0.17 g/24 h; p = 0.011).

A highly significant statistical relationship was found between the control and the study group in such parameters as body weight ( p < 0.012), height ( p < 0.0001), and BMI ( p < 0.001).