Excerpts

In MAC-T cells, siRNA 416 had a highly significant interference effect on the COL6A1 gene, with an interference efficiency of 68.3% to 75.1% at the mRNA level ( Figure 3 a; p < 0.01).

Transient overexpression of miR156x with OD600 concentrations of 0.5, 0.7, and 0.9 in mulberry seedlings resulted in a highly significant increase in leaf POD activity from days 2 to 5 ( p ≤ 0.01).

Postoperative anti-glaucoma medications showed a highly significant intergroup difference ( p = 0.01), being most frequent in RRD (56.9%), followed by dropped IOL/lens (50.0%).

During sibutramine therapy, expression of miR-378 in SAT tended to increase but did not reach statistical significance, while in plasma, a reliable increase in the miR-378 level was revealed ( p = 0.01) ( Figure 1 C,D).

Levels of significance were expressed as significant, p < 0.05 and highly significant, p < 0.01, respectively. 5.

Eight proteins showed levels with statistically significant differences between ND_ and R_T0 saliva, with four of them exhibiting a highly significant alteration (*** p -value < 0.01), namely, PRDX2, PSMB1, CYCS, and TMOD3.

The results of a Student’s t -test showed a highly significant difference ( p < 0.01) between the sorption behavior of peanut protein to PCT at a nearly neutral pH of 6.8 and pH 5.5, even though the difference in pH was only 1.3.

In terms of inflammatory and oxidative stress markers, L-proline and 9(S)-HODE both showed highly significant correlations with ATP levels ( p < 0.01) and moderate associations with IL-1β ( p < 0.05).

Statistical analysis indicated that the lesion length reduction in all three transgenic lines was highly significant (paired t -test, p < 0.01, Figure 4 B), suggesting that ZmRACK1 overexpression enhanced maize resistance against the leaf blight pathogen, E. turcicum . 2.5.

The results showed a highly significant correlation between sphingolipid metabolism and key metabolites in pyrimidine metabolism ( p < 0.01, Figure S3 ).

All six time points show p -values below 0.05, with most comparisons demonstrating highly significant differences ( p < 0.01, Figure 3 B).

For all assays, differences between samples or time points were regarded as significant if p ≤ 0.05 and highly significant if p ≤ 0.01.

A highly significant difference ( p ≤ 0.01) was noted only between M from SCC and CRC groups (difference of 13.7 IU/L) ( Figure 1 ).

Statistically, “**” indicates highly significant differences ( p < 0.01), “*” indicates significant differences ( p < 0.05), and “N.S.” indicates non-significant differences ( p > 0.05). 5.

The resulting differences were stated as significant if the p -values were less than 0.05 (* p ≤ 0.05) or as highly significant for p -values less than 0.01 (** p ≤ 0.01) or less than 0.001 (*** p ≤ 0.001).

The impact of depth was particularly pronounced for indel calling, as evidenced by both highly significant p -values ( p < 0.01) and substantially larger effect size estimates compared to those observed for SNV calling.

Differential expression of CD58, CD304, and CD73 in diagnostic samples was highly significant ( p < 0.01) between pre-B-I, pre-B-II, immature B cells, and BCP-ALL blasts.

Since these drugs are known to induce apoptosis, we next measured the specific activity of caspases 3/7, proteases that are activated in both intrinsic and extrinsic apoptosis pathways, and found that it increased to a lesser extent in GNPTAB KO HeLa cells compared to control cells after the indicated treatments ( Figure 1 B, p < 0.01, except for paclitaxel, for which the difference did not reach statistical significance).

Differences were considered statistically significant at p < 0.05 and highly significant at p < 0.01.

The circles in the figure represented the GO classification in which the differential proteins are located, with red representing extremely significant DEPs ( p value ≤ 0.01), yellow representing significant differential proteins ( p value ≤ 0.05), and blue representing non-significant enrichment.

The expression of SmaTLR22 continuously increased after poly (I:C) stimulation, showing extremely significant upregulation at 24 and 48 hpi ( p < 0.01). 3.

The average body weight of HFD and SND rabbits exhibited significant divergence after 2 weeks ( p < 0.05), and this discrepancy became highly significant at 3–5 weeks ( p < 0.01).

In the case of all tested strains, the combined use of antibiotics (AMC, AMP, and IMP) and phages (2e and 3e) resulted in a highly significant reduction in the number of resistant variants compared to those obtained after the use of either agent alone ( p ≤ 0.01 or lower).

After the inhibition of HSD17B12 ( Figure 5 F), the proliferation rate of cells was higher than that of the shRNA-NC group and reached a highly significant level ( p < 0.01) at 24 h.

Statistical analyses were performed using one-way ANOVA, and it was considered significant when p < 0.05 (*) or considered extremely significant when p < 0.01 (**).