Barely Significant

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It can be seen from the data presented in Figure 4 a that the TN concentration in the high flow season from 2019 to 2021 showed a decreasing trend first (May to August during dry and normal years, and May to June during the wet year) and then an increasing trend, which is opposite to the change in rainfall and runoff.
Figure 10 shows that Type 2, Type 6, and Type 8, having something in common in the low level of driving forces, are the main types with an increasing trend, and these three types of prefecture-level cities are spatially clustered and contiguous in 2019 and 2000, though the specific prefecture-level cities in each type vary considerably.
In practice, however, this would require data regarding clearly defined diseases, such as atherosclerosis, which is rare, while related endpoints, such as the pathology of the heart and vascular system, or blood cholesterol, usually did not show a significant trend in the studies we reviewed.
All the other dimensions received a bad evaluation by users over the system usage, with small fluctuations from T1 to T2 that only had an increasing trend for “efficiency”, reflecting a slight improvement of the system, while “attractiveness”, “dependability”, and “stimulation” decreased markedly.