Excerpts

The overall pooled analysis showed a trend toward clinical improvement that was not statistically significant (MD: 0.70; 95% CI: -0.55, 1.95; p = 0.2682).

VD rates after myomectomy showed a trend toward LM (37.9% vs. 32.1%; RR = 1.18; P = 0.27), while CS rates were lower in LM (47.4% vs. 57.8%; RR = 0.82; P = 0.17); however, both findings lacked statistical significance.

Male subjects in the active arm had a positive trend of improvement in CDT scores, with the mean CDT value going up from 3.4 ± 1.4 at week 0 to 3.8 ± 1.4 (p = .29) at week 8.

Renal insufficiency showed a trend toward increased mortality risk (ORa=2.1; 95% CI: 0.5-8.7; p=0.298), as did NYHA functional class IV (ORa=2.8; 95% CI: 0.6-12.4; p=0.184), but neither achieved statistical significance, likely due to the relatively small number of mortality events (n=16) limiting statistical power.

Similarly, serum albumin levels showed a nonsignificant trend toward higher values in the sarcopenic group (3.97 ± 0.77 g/dL vs. 3.74 ± 0.81 g/dL; p = 0.302).

Although severe vision loss (NOIAA/OACR) showed a trend toward association with a positive biopsy (OR = 2.00), this association was not statistically significant (p = 0.32).

In the MM subgroup, the difference in LOS, although not statistically significant, showed a trend toward longer stays in malnourished patients (39.00 days vs. 18.03 days, p = 0.3337) (Figure 1 ).

Among patients with unilateral ANH, the current data indicate a possible trend of the left kidney (73.5%) being more impacted than the right kidney (26.5%; chi-square test value = 0.907, p = 0.341), although the data are not statistically significant.

Despite the clear impact of CIN on morbidity, healthcare costs, and hospital readmission, this study did not identify a significant trend in overall mortality (p = 0.352).

Although the RA group showed a favorable trend, the difference was not statistically significant (χ2(2) = 2.01, p = 0.365).

At the three-month follow-up, no statistically significant between-group difference was apparent (MD=-1.3; 95% CI: -4.16 to 1.56; p=0.37; I2=34.96%).

Comorbidities overall were not significantly significant (P=0.38, OR=0.68, 95% CI 0.29 to 1.61), an associated condition like acne was statistically significant in the PCOS group (P=0.02).

Although pain during the first steps in the morning showed a trend favouring the ESWT group, statistical significance was not reached (P = 0.39) (Figure 2 ).

A highly significant negative correlation between SBS & etching pattern (P = 0.42) was observed among intra-group correlation.

In our multivariable model, a nonsignificant trend toward higher risk with mastectomy (HR: 2.27, p=0.50) further supports that the extent of resection alone does not drive survival.

In this study, female gender was associated with SVR failure (OR: 3.20) but was not significantly significant (p=0.517), which may be due to the low sample size.

Regression estimates showed a trend toward a prolonged time to recovery with LDN (aHR 0.89; 95% CI: 0.63-1.28, p=0.54) and a trend toward a decrease in the day of disease recovery and LOE with colchicine (aHR 1.32; 95% CI: 0.91-1.82, p=0.16).

Even though an increasing trend was noted among the c-MYC positive group, no statistically significant correlation was obtained between c-MYC expression and histological grade (p = 0.549).

In five-year DFS patients with LNR cut-off value ≤ 0.02 were 86% and LNR cut-off value > 0.02 were 14% (statistically borderline significance, p=0.55) (Table 3 ).

The reoperation rate at one year was lower in the CCS group at 6.3% (n = 2); however, this was not significantly significant (p = 0.588).

However, only CPB time >180 min was highly significant with OR 16.2, p=00.6 compared to CPB time 121-180 min OR 2.3, p=0.29 and CPB time 91-120 min OR 1.2, p=0.84.

Patients with ER-negative tumors showed a trend toward poorer five-year survival than for those with ER-positive tumors, DFS was 56% vs. 83% (p = 0.609) and OS was 50% vs. 71% (p = 0.646), respectively.

In the Asian or Pacific Islander population, AAMR decreased from 12.90 in 1999 to 6.00 in 2023, with significant declines from 1999 to 2010 (APC: -2.85%, 95% CI: -4.46 to -1.21; p=0.002) and 2010 to 2015 (APC: -8.37%, 95% CI: -14.47 to -1.84; p=0.016), followed by a nonsignificant trend from 2015 to 2023 (APC: 0.38%, 95% CI: -1.76 to 2.58; p=0.713).

However, the mean initial HCT exhibited a highly significant negative association (B = -2.328, p = 0.721), resulting in an aOR of 0.098 (95% CI: 0.000-35004.598).

Patients with GC showed a trend toward better prognosis (p=0.812) (Figure 5C ).